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Filtering by: Department Dept. of Biochemistry and Molecular Biology Remove constraint Department: Dept. of Biochemistry and Molecular Biology Collection Scholars Archive Remove constraint Collection: Scholars Archive Resource type dissertation Remove constraint Resource type: dissertation
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  1. Transplantation of Differentiated iPSCs as a Treatment Strategy for Glaucoma

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  2. Crystallographic studies on the multidrug-binding transcription activator BmrR, from B. subtilis, and E. coli purine repressor

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  3. Two mechanisms of host control of human immunodeficiency virus type 1 (HIV-1) infection : analyses of HIV-1s viral infectivity factor and biochemical characterization of inhibition of chemokine receptor signaling by viral envelope gp120

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  4. Studies of the active site of the HIV-1 fusion cofactor CCR5

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  5. Synthesis and biophysical characterization of collagen-like peptides : glycosylation-induced stabilization of the triple-helix

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  6. Molecular and biochemical characterization of the adenosine

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  7. Ligand recognition by prokaryotic transcription regulators

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  8. Structure-function studies of Na, K-ATPase using site-directed mutagenesis and chemical modification

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  9. Crystallographic studies on the multidrug transporter activation protein n-terminus from Bacillus subtilis

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  10. Structural studies on HPrK

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  11. Identification and characterization of a UV-responsive P53 serine 392 kinase complex

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  12. Priming of therapeutic T cells for adoptive immunotherapy

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  13. Dissecting the pathology of pseudoachondroplasia through structural and biosynthesis studies on cartilage oligomeric matrix protein

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  14. Molecular mechanism of dephosphorylation by dual-specificity phosphatases

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  15. Structural dynamics of rhodopsin : relationships between retinal Schiff base integrity and receptor signaling states

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  16. Structure-function analysis of the inosine-guanosine transporter from Leishmania donovani using reverse and forward genetics

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  17. SCF[superscript Grr1]-mediated ubiquitination of Gis4 Modulates Glucose response in yeast

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  18. Molecular mechanisms of copper transfer from the metallochaperone atox1 to the Wilson disease protein

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  19. Understanding the constraints of sequence, structure, and energetics on intramolecular chaperone-mediated protein folding

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  20. Receptor binding interactions of herstatin and its intron-encoded domain

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  21. Molecular characterization of copper uptake into eukaryotic cells mediated by human copper transporter 1

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  22. Structural studies on the MarR family : crystal strcutrues [i.e. structures] of OhrR-DNA and SlyA-inducer complexes

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  23. A genetic analysis of the purine salvage pathway of Leishmania donovani

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  24. Analysis of substitutions of glutamate 90 and glutamate 120 in the multidrug resistance regulator QacR reveal new modes of ligand binding

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  25. Dynamics of arrestin-rhodopsin interactions

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  26. DNA recognition by prokaryotic transcriptional regulators

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  27. Regulation of transferrin receptor 2 stability and trafficking in hepatoma cells

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  28. The dopamine ?-hydroxylase gene : utilization of translation initiation codons and regulatory elements involved in transcription

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  29. A study of the role of matrix metalloproteinases and their inhibitors in a treatment of glaucoma

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  30. Consequences of proteolytic modification of the molecular chaperone alpha-crystallin

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  31. Molecular cloning and functional expression of the S-adenosylmethionine decarboxylase gene of Leishmania donovani and Trypanosoma brucei

    Mc87pq395?file=thumbnail
  32. Crystallographic studies on the purine repressor, an Escherichia coli DNA-binding protein

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  33. Non-enzymatic oxidative deamination of lysines to allysines by orthoquinones

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  34. A characterization of two enzymes in the methionine salvage pathway : methylthioadenosine

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  35. The characterization of gelatinase inhibition and the involvement of the matrix metalloproteinases and their inhibitors in glaucoma and a retinal degeneration

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  36. The purine salvage pathway as a target for structure-based drug design in the intracellular parasites Leishmania donovani, Mycobacterium avium and Mycobacterium tuberculosis

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  37. Phosphoribosyltransferases in Toxoplasma gondii : targets for structure-based inhibitor design

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  38. Kinetic and thermodynamic characterization of matrix metalloproteinase-3, stromelysin, and its effect in an ocular anterior segment organ culture system

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  39. Structural organization of pulmonary surfactant films

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  40. Antimalarial and antileishmanial action of xanthones : host-parasite differences in heme metabolism as chemotherapeutic targets

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  41. Cloning, expression and functional characterization of the mitochondrial carnitine palmitoyltransferases

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  42. Cloning and characterization of cellobiose dehydrogenase from Phanerochaete chrysosporium

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  43. The Mechanism of type I collagen crosslinking with catechol derivatives

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  44. Structure, function and expression of two protein kinasesa dissertation

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  45. Biochemical and pharmacological characterization of sigma binding sites in NCB-20 cells and study of the inhibition of agonist-stimulated phosphoinositide hydrolysis by sigma compounds

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  46. A Model of connective tissue microfibrils : structural studies of fibrillin fragments

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  47. Characterization of the human motilin gene

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  48. Amplification and molecular cloning of the inosine 5-monophosphate dehydrogenase gene of Leishmania donovani and Trypanosoma brucei

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  49. Expression and characterization of a matrix metalloproteinase (stromelysin) using a retroviral gene transfer system

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  50. Molecular characterization of g-protein coupled receptors

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