1.
Mucosal-associated invariant T (MAIT) cells are an innate-like T cell subset important in the early response to bacterial and viral lung pathogens. Upon activation, MAIT [...]
2024-12-20 | Dissertation |
2.
This work explores immunity induced by the yellow fever vaccine, 17D, efficacy. First, we provide a comprehensive review of breakthrough yellow fever infection. Next, we [...]
2024-10-09 | Dissertation |
3.
In this dissertation I explore applications of antibodies and alpaca-derived antibody fragments, known as VHHs, to understand severe acute respiratory associated coronavi [...]
2024-09-18 | Dissertation |
4.
Tuberculosis (TB) is a devastating illness. In the search for novel anti-TB therapies, there is growing interest in host-directed therapy (HDT), which seeks to synergize [...]
2024-02-16 | Dissertation |
5.
Dendritic cells (DC) are mediators between innate and adaptive immune responses to pathogens and tumors. DC development is determined by signaling through the receptor ty [...]
2024-02-24 | Dissertation |
6.
While it is becoming more appreciated that non-hematopoietic cells within barrier tissues participate in and modulate the host immune response, their roles are still inco [...]
2023-12-08 | Dissertation |
7.
Here, I present a comprehensive assay termed UbiReal for monitoring each step of the Ub signaling cascade, including linkage-specific polyUb ligation and deubiquitination [...]
2023-11-24 | Dissertation |