TY - GEN AB - Sensory processing disorder (SPD) is characterized by impairments in sensory processing, though the underlying neural correlates of these symptoms are largely unknown. Additionally, it is unclear what factors might lead to the development of SPD. Children with autism spectrum disorder (ASD) often report a SPD, so the two may share similar causes. Predictors of ASD include prenatal exposure to a Western-style diet (WSD), increased maternal adiposity, and increased maternal inflammation. These factors may contribute to ASD by stimulating neuroinflammation and thereby impacting microglia-mediated processes of neural circuit formation. However, these prenatal exposures and neuroinflammatory processes of circuit restructuring have not been sufficiently explored in SPD. The goal of the present work is to advance what is known about the etiology of SPD. AD - Oregon Health and Science University AU - Papadakis, Samantha DA - 2023 DO - 10.6083/bg257f801 DO - DOI ED - Sullivan, Elinor ED - Fair, Damien ED - Advisor ED - Mentor ED - Advisor ED - Mentor ID - 10055 KW - Neurodevelopmental Disorders KW - Magnetic Resonance Imaging KW - Prenatal Exposure Delayed Effects KW - Sensation Disorders KW - Macaca KW - Child KW - western diets L1 - https://digitalcollections.ohsu.edu/record/10055/files/Papadakis.Samantha.2023.pdf L2 - https://digitalcollections.ohsu.edu/record/10055/files/Papadakis.Samantha.2023.pdf L4 - https://digitalcollections.ohsu.edu/record/10055/files/Papadakis.Samantha.2023.pdf LK - https://digitalcollections.ohsu.edu/record/10055/files/Papadakis.Samantha.2023.pdf N2 - Sensory processing disorder (SPD) is characterized by impairments in sensory processing, though the underlying neural correlates of these symptoms are largely unknown. Additionally, it is unclear what factors might lead to the development of SPD. Children with autism spectrum disorder (ASD) often report a SPD, so the two may share similar causes. Predictors of ASD include prenatal exposure to a Western-style diet (WSD), increased maternal adiposity, and increased maternal inflammation. These factors may contribute to ASD by stimulating neuroinflammation and thereby impacting microglia-mediated processes of neural circuit formation. However, these prenatal exposures and neuroinflammatory processes of circuit restructuring have not been sufficiently explored in SPD. The goal of the present work is to advance what is known about the etiology of SPD. PB - Oregon Health and Science University PY - 2023 T1 - Prenatal exposure to a western-style diet: impacts to sensory connectivity and neuroinflammation in the context of sensory processing disorder TI - Prenatal exposure to a western-style diet: impacts to sensory connectivity and neuroinflammation in the context of sensory processing disorder UR - https://digitalcollections.ohsu.edu/record/10055/files/Papadakis.Samantha.2023.pdf Y1 - 2023 ER -