000010055 001__ 10055
000010055 005__ 20240124114335.0
000010055 0247_ $$2DOI$$a10.6083/bg257f801
000010055 037__ $$aETD
000010055 245__ $$aPrenatal exposure to a western-style diet: impacts to sensory connectivity and neuroinflammation in the context of sensory processing disorder
000010055 260__ $$bOregon Health and Science University
000010055 269__ $$a2023
000010055 336__ $$aDissertation
000010055 502__ $$bPh.D.
000010055 520__ $$aSensory processing disorder (SPD) is characterized by impairments in sensory processing, though the underlying neural correlates of these symptoms are largely unknown. Additionally, it is unclear what factors might lead to the development of SPD. Children with autism spectrum disorder (ASD) often report a SPD, so the two may share similar causes. Predictors of ASD include prenatal exposure to a Western-style diet (WSD), increased maternal adiposity, and increased maternal inflammation. These factors may contribute to ASD by stimulating neuroinflammation and thereby impacting microglia-mediated processes of neural circuit formation. However, these prenatal exposures and neuroinflammatory processes of circuit restructuring have not been sufficiently explored in SPD.  The goal of the present work is to advance what is known about the etiology of SPD.
000010055 542__ $$fIn copyright - single owner
000010055 650__ $$aNeurodevelopmental Disorders$$040742
000010055 650__ $$aMagnetic Resonance Imaging$$021747
000010055 650__ $$aPrenatal Exposure Delayed Effects$$024568
000010055 650__ $$aSensation Disorders$$025869
000010055 650__ $$aMacaca$$021722
000010055 650__ $$aChild$$016462
000010055 6531_ $$awestern diets
000010055 691__ $$aSchool of Medicine$$041369
000010055 692__ $$aDepartment of Behavioral Neuroscience$$041394
000010055 7001_ $$aPapadakis, Samantha L.
000010055 8564_ $$938814dfe-a17f-4940-9897-f792024fc270$$s41351620$$uhttps://digitalcollections.ohsu.edu/record/10055/files/Papadakis.Samantha.2023.pdf
000010055 905__ $$a/rest/prod/bg/25/7f/80/bg257f801
000010055 909CO $$ooai:digitalcollections.ohsu.edu:10055$$pstudent-work
000010055 980__ $$aTheses and Dissertations