000010072 001__ 10072 000010072 005__ 20240125143600.0 000010072 0247_ $$2DOI$$a10.6083/tt44pn78q 000010072 037__ $$aIR 000010072 245__ $$aAortic sinus morphology correlates with clinical features in patients with bicuspid aortic valve 000010072 260__ $$bOregon Health and Science University 000010072 269__ $$a2023 000010072 336__ $$aCapstone 000010072 502__ $$gMedicine (Undergraduate Medical Education) 000010072 502__ $$bM.D. 000010072 520__ $$aBicuspid Aortic Valve (BAV) is the most common congenital heart malformation that lacks BAV-specific prognostic markers other than the development of aortic stenosis. Over the past few decades, it has been shown that mechanical and genetic factors both contribute to pathology associated with BAV. The relationship between aortic sinus morphology, cardiac remodeling, and clinical status has never been studied. We propose the development of an analytic aortic valve based on the shape and relationships between the aortic sinuses. 000010072 540__ $$fCC BY 000010072 650__ $$aAortic Valve Stenosis$$014963 000010072 650__ $$aBicuspid Aortic Valve Disease$$013334 000010072 6531_ $$anew york heart association 000010072 691__ $$aSchool of Medicine$$041369 000010072 7001_ $$aDally, Matthew$$uOregon Health and Science University$$041354 000010072 7201_ $$aBroberg, Craig$$uOregon Health and Science University$$041354$$7Personal$$eCo-PI 000010072 7201_ $$aMuralidaran, Ashok$$uOregon Health and Science University$$041354$$7Personal$$eCo-PI 000010072 7201_ $$aHan, Xiao-Yue$$uOregon Health and Science University$$041354$$7Personal$$eCo-PI 000010072 7201_ $$aKhanjian, Roupen$$uUniversity of California Santa Barbara$$7Personal$$eCo-PI 000010072 7201_ $$aSilberbach, Michael$$uOregon Health and Science University$$041354$$7Personal$$eCo-PI 000010072 8564_ $$9fbdc9b04-a34a-407c-9f1f-70edd8cc5586$$s549465$$uhttps://digitalcollections.ohsu.edu/record/10072/files/Dally.Matthew.2023.pdf 000010072 905__ $$a/rest/prod/tt/44/pn/78/tt44pn78q 000010072 909CO $$ooai:digitalcollections.ohsu.edu:10072$$pstudent-work 000010072 980__ $$aScholarly Project Capstones