TY - THES AB - Norepinephrine (NE) is a neuromodulator that alters processing in nearly every brain area, leading to dynamic changes in behavior. NE plays a vital role in arousal, attention, stress, and memory formation through widespread neuronal projections. In this work, I will discuss the historical development of the NE research field, building to a picture of the modern view of diverse NE cell types within and around the LC. I will further document the experimental efforts by myself and my colleagues over the last two years toward elucidating this diversity of cellular function in the NE signaling network. AU - Culp, Amelia DA - 2023 DO - 10.6083/kp78gh077 DO - DOI ID - 10113 KW - Attention KW - Locus Coeruleus KW - Norepinephrine KW - Arousal L1 - https://digitalcollections.ohsu.edu/record/10113/files/Culp.Amelia.2023.pdf L2 - https://digitalcollections.ohsu.edu/record/10113/files/Culp.Amelia.2023.pdf L4 - https://digitalcollections.ohsu.edu/record/10113/files/Culp.Amelia.2023.pdf LK - https://digitalcollections.ohsu.edu/record/10113/files/Culp.Amelia.2023.pdf N2 - Norepinephrine (NE) is a neuromodulator that alters processing in nearly every brain area, leading to dynamic changes in behavior. NE plays a vital role in arousal, attention, stress, and memory formation through widespread neuronal projections. In this work, I will discuss the historical development of the NE research field, building to a picture of the modern view of diverse NE cell types within and around the LC. I will further document the experimental efforts by myself and my colleagues over the last two years toward elucidating this diversity of cellular function in the NE signaling network. PB - Oregon Health and Science University PY - 2023 T1 - Cell type diversity in the norepinephrine signaling network TI - Cell type diversity in the norepinephrine signaling network UR - https://digitalcollections.ohsu.edu/record/10113/files/Culp.Amelia.2023.pdf Y1 - 2023 ER -