000010113 001__ 10113 000010113 005__ 20231129124954.0 000010113 0247_ $$2DOI$$a10.6083/kp78gh077 000010113 037__ $$aETD 000010113 245__ $$aCell type diversity in the norepinephrine signaling network 000010113 260__ $$bOregon Health and Science University 000010113 269__ $$a2023 000010113 336__ $$aThesis 000010113 502__ $$bM.S. 000010113 520__ $$aNorepinephrine (NE) is a neuromodulator that alters processing in nearly every brain area, leading to dynamic changes in behavior. NE plays a vital role in arousal, attention, stress, and memory formation through widespread neuronal projections. In this work, I will discuss the historical development of the NE research field, building to a picture of the modern view of diverse NE cell types within and around the LC. I will further document the experimental efforts by myself and my colleagues over the last two years toward elucidating this diversity of cellular function in the NE signaling network. 000010113 650__ $$a Attention$$015203 000010113 650__ $$aLocus Coeruleus$$021606 000010113 650__ $$a Norepinephrine$$022999 000010113 650__ $$aArousal$$015068 000010113 691__ $$aSchool of Medicine$$041369 000010113 692__ $$aVollum Institute$$041509 000010113 7001_ $$aCulp, Amelia 000010113 8564_ $$9070f9ee6-5869-4ffd-b76c-a0ee25109ac3$$s6984761$$uhttps://digitalcollections.ohsu.edu/record/10113/files/Culp.Amelia.2023.pdf 000010113 905__ $$a/rest/prod/kp/78/gh/07/kp78gh077 000010113 909CO $$ooai:digitalcollections.ohsu.edu:10113$$pstudent-work 000010113 980__ $$aTheses and Dissertations