000010143 001__ 10143 000010143 005__ 20240124114338.0 000010143 0247_ $$2DOI$$a10.6083/vq27zp152 000010143 037__ $$aETD 000010143 245__ $$aEvaluation of tools for functional inference in the pediatric gut microbiome 000010143 260__ $$bOregon Health and Science University 000010143 269__ $$a2023 000010143 336__ $$aThesis 000010143 520__ $$aThere is growing appreciation for the role that commensal microorganisms play in affecting host health and disease, especially in humans. Comprised of bacteria, fungi, viruses, and archaea, the human gut harbors a diverse community of microorganisms, referred to as the gut microbiome, that contribute to metabolism and immunity, among other vital functions1. Altered gut microbiome composition has been associated with various types of diseases including gastrointestinal diseases, metabolic diseases, neuropsychiatric diseases, and cancers. 000010143 650__ $$aGastrointestinal Microbiome$$011348 000010143 650__ $$aChild$$016462 000010143 650__ $$aBenchmarking$$032042 000010143 650__ $$aComputational Biology$$031511 000010143 650__ $$a Microbiota$$040384 000010143 6531_ $$ahuman 000010143 691__ $$aSchool of Medicine$$041369 000010143 7001_ $$aHammer, Matthew 000010143 8564_ $$98db99312-f463-4dce-92bc-f2c91c7ed061$$s916783$$uhttps://digitalcollections.ohsu.edu/record/10143/files/Hammer.Matthew.2023.pdf 000010143 905__ $$a/rest/prod/vq/27/zp/15/vq27zp152 000010143 909CO $$ooai:digitalcollections.ohsu.edu:10143$$pstudent-work 000010143 980__ $$aTheses and Dissertations