Aldo-Keto Reductases

Aldo-Keto Reductase
Aldo-Keto Reductase Family
Aldo-Keto Reductase Superfamily
Aldo Keto Reductase
Aldo Keto Reductase Family
Aldo Keto Reductase Superfamily
Aldo Keto Reductases
Reductase, Aldo-Keto
Reductases, Aldo-Keto

A family of NADPH-dependent oxidoreductases that reduce carbonyl substrates including sugar-aldehydes, KETOSTEROIDS; keto-prostaglandins, and QUINONES. They are monomers of approximately 37 KDa and are characterized by a parallel beta-8 (BETA SHEET)-alpha 8 (ALPHA HELICES)-barrel structure that contains the NADP binding site. This conformation favors aromatic and apolar substrates.
2018