TY - THES AB - There has been a controversy among both clinicians and physiologists for a long time concerning the effects of various toxins on the thyroid gland. On one side, we have the evidence from exhaustive work done by McCarrison, in 1911, to show the feeding of fecal extracts and fecal residues to rats produced thyroid changes, loosely classed as “goitre”, in 100% of the animals. So closely to the symptoms of acute tuberculosis and acute toxic goitre resemble each other in the first stages that it has been definitively established by Goetsch, in the 1919, and Otis, in 1920, that the thyroid hypersecretion is involved in both. AD - University of Oregon AU - Jones, Lester T. DA - 1923 DO - 10.6083/M4M043BN DO - DOI ID - 181 KW - Thyroid Gland KW - Feces KW - Endotoxins KW - Goiter KW - Tuberculosis KW - Rats KW - Models, Animal L1 - https://digitalcollections.ohsu.edu/record/181/files/181_etd.pdf L2 - https://digitalcollections.ohsu.edu/record/181/files/181_etd.pdf L4 - https://digitalcollections.ohsu.edu/record/181/files/181_etd.pdf LA - eng LK - https://digitalcollections.ohsu.edu/record/181/files/181_etd.pdf N2 - There has been a controversy among both clinicians and physiologists for a long time concerning the effects of various toxins on the thyroid gland. On one side, we have the evidence from exhaustive work done by McCarrison, in 1911, to show the feeding of fecal extracts and fecal residues to rats produced thyroid changes, loosely classed as “goitre”, in 100% of the animals. So closely to the symptoms of acute tuberculosis and acute toxic goitre resemble each other in the first stages that it has been definitively established by Goetsch, in the 1919, and Otis, in 1920, that the thyroid hypersecretion is involved in both. PB - University of Oregon PY - 1923 T1 - Acute changes in the thyroid gland produced by fecal toxins TI - Acute changes in the thyroid gland produced by fecal toxins UR - https://digitalcollections.ohsu.edu/record/181/files/181_etd.pdf Y1 - 1923 ER -