000000021 001__ 21
000000021 005__ 20260513072057.0
000000021 0247_ $$2DOI$$a10.6083/M48G8HMF
000000021 037__ $$aETD
000000021 245__ $$aGas/particle partitioning of ammonia and nicotine in mainstream tobacco smoke and its implications of acid/base chemistry of tobacco smoke
000000021 260__ $$bOregon Health and Science University
000000021 269__ $$a2006
000000021 336__ $$aDissertation
000000021 502__ $$bPh.D.
000000021 520__ $$aNicotine addiction and the sensory impact of tobacco smoke are strongly influenced by the fraction of nicotine present in its free-base form. This work examines the acid–base chemistry governing the interdependent gas/particle partitioning of nicotine and ammonia in mainstream tobacco smoke, motivated by evidence that ammonia-producing additives are used to enhance smoke “impact.” Using established acid–base and partitioning theory, equations describing the coupled behavior of nicotine and ammonia were derived, and key partitioning and activity coefficients were estimated from existing data. The model predicts a linear correlation between nicotine and ammonia partitioning, improving understanding of how additives influence nicotine chemistry and smoke characteristics.
000000021 540__ $$fCC BY
000000021 542__ $$fIn copyright - single owner
000000021 650__ $$aAmmonia$$014606
000000021 650__ $$aNicotine$$022904
000000021 650__ $$aTobacco$$027130
000000021 650__ $$aTobacco Smoke Pollution$$027132
000000021 650__ $$aTobacco Use Disorder$$027133
000000021 691__ $$aOGI School of Science and Engineering$$041365
000000021 692__ $$aOGI Department of Environmental Science and Engineering$$041415
000000021 7001_ $$aChen, Cai$$uOregon Health and Science University$$041354
000000021 7201_ $$aPankow, James$$uOregon Health and Science University$$041354$$7Personal$$eAdvisor
000000021 8564_ $$9458e13e1-ec7c-44e3-b31e-43a14dda597d$$s1499462$$uhttps://digitalcollections.ohsu.edu/record/21/files/21_etd.pdf$$ePublic$$2ce2a9b89b0071d281aea2f30d69400cd$$31
000000021 901__ $$a&lt;p&gt;These documents are archival records. They are retained for historical reference only. &lt;/p&gt;&lt;p&gt;&lt;b&gt;Need an accessible version? Use the ‘Get Accessible Copy’ link above.&lt;/b&gt;&lt;/p&gt;
000000021 905__ $$a/rest/prod/dr/26/xx/36/dr26xx36k
000000021 909CO $$ooai:digitalcollections.ohsu.edu:21$$pstudent-work
000000021 956__ $$aGet Accessible Copy$$uhttps://ohsu.libwizard.com/f/requestaccessibledocument
000000021 980__ $$aTheses and Dissertations