@article{ETD,
      recid = {2159},
      author = {Scarborough, John},
      title = {Hair-cell adaptation motors: a chemical-genetic approach},
      publisher = {Oregon Health and Science University},
      school = {Ph.D.},
      address = {2006},
      number = {ETD},
      abstract = {Sensory hair cells adapt to sustained mechanical  stimulation through Ca²⁺-dependent closure of transduction  channels via fast and slow mechanisms. Using genetically  sensitized mouse models, this study examined the roles of  myosin-1c (Myo1c) and myosin-7a (Myo7a) in hair-cell  adaptation. Pharmacological inhibition of Myo1c blocked  both fast and slow adaptation in vestibular hair cells,  indicating a mechanical role for Myo1c in both processes.  Studies of Myo7a suggest it is essential for proper  transduction and bundle organization, highlighting distinct  myosin contributions to hair-cell adaptation and auditory  function.},
      url = {http://digitalcollections.ohsu.edu/record/2159},
      doi = {https://doi.org/10.6083/M4VM49J6},
}