000002160 001__ 2160
000002160 005__ 20260505134013.0
000002160 0247_ $$2DOI$$a10.6083/M4QV3JS1
000002160 037__ $$aETD
000002160 245__ $$aLow molecular weight hyaluronic acid increases CD44 expression by oligodendrocytes and enhances inflammation
000002160 260__ $$bOregon Health and Science University
000002160 269__ $$a2006
000002160 336__ $$aThesis
000002160 502__ $$bM.S.
000002160 502__ $$gCell & Developmental Biology (sunsetting)
000002160 520__ $$aMultiple sclerosis (MS) is a chronic autoimmune disease characterized by immune-mediated destruction of myelin in the central nervous system, resulting in disrupted nerve conduction and progressive neurological disability. Disease manifestations include sensory, motor, visual, and autonomic dysfunction. MS prevalence varies with geography, genetics, sex, and environmental factors. Although the precise cause is unknown, evidence supports a complex interaction between genetic susceptibility, environmental triggers, and immune dysregulation that leads to inflammatory demyelination and axonal injury.
000002160 540__ $$fCC BY
000002160 542__ $$fIn copyright - single owner
000002160 650__ $$aMultiple Sclerosis$$022506
000002160 650__ $$aAntigens$$014884
000002160 650__ $$aMyelin Sheath$$022587
000002160 650__ $$aT-Lymphocytes$$026731
000002160 650__ $$aOligodendroglia$$023183
000002160 650__ $$aEncephalomyelitis$$018392
000002160 650__ $$aHyaluronic Acid$$020392
000002160 650__ $$aAutoimmune Diseases of the Nervous System$$032285
000002160 650__ $$aHyaluronan Receptors$$031234
000002160 650__ $$aCentral Nervous System$$016312
000002160 691__ $$aSchool of Medicine$$041369
000002160 692__ $$aDepartment of Cell, Developmental and Cancer Biology$$041399
000002160 7001_ $$aKassler, Susannah$$uOregon Health and Science University$$041354
000002160 7201_ $$aSherman, Larry$$uOregon Health and Science University$$041354$$7Personal$$eCo-Mentor
000002160 7201_ $$aBebo, Bruce$$uOregon Health and Science University$$041354$$7Personal$$eCo-Mentor
000002160 8564_ $$9ec33c21f-5fc1-47f7-b16a-17e96c082d10$$s3187929$$uhttps://digitalcollections.ohsu.edu/record/2160/files/2889_etd.pdf$$ePublic$$237edd8f9ea89a898605983bdac10e019$$31
000002160 901__ $$a<p>These documents are archival records. They are retained for historical reference only. </p><p><b>Need an accessible version? Use the ‘Get Accessible Copy’ link above.</b></p>
000002160 905__ $$a/rest/prod/1v/53/jx/11/1v53jx11j
000002160 909CO $$ooai:digitalcollections.ohsu.edu:2160$$pstudent-work
000002160 956__ $$aGet Accessible Copy$$uhttps://ohsu.libwizard.com/f/requestaccessibledocument
000002160 980__ $$aTheses and Dissertations