000002166 001__ 2166
000002166 005__ 20260429162528.0
000002166 0247_ $$2DOI$$a10.6083/M4ZC814J
000002166 037__ $$aETD
000002166 245__ $$aNeural networks of top-down and bottom-up attention in early onset blindness
000002166 260__ $$bOregon Health and Science University
000002166 269__ $$a2006
000002166 336__ $$aDissertation
000002166 502__ $$bPh.D.
000002166 502__ $$gBehavioral & Systems Neuroscience
000002166 520__ $$aEarly blindness is associated with cross‑modal reorganization of occipital cortex, yet the functional role of this activity remains unclear. This dissertation examined whether top‑down and bottom‑up attentional mechanisms modulate occipital activation in early blind (EB) individuals and whether such modulation relates to enhanced non‑visual performance. Using event‑related fMRI and auditory, tactile, and bimodal oddball tasks, results showed that both salient distractors and selectively attended targets evoked occipital responses in EB participants, but not sighted controls. Findings indicate that attentional processes contribute to occipital cross‑modal reorganization and may underlie behavioral advantages observed in early blindness.
000002166 540__ $$fCC BY
000002166 542__ $$fIn copyright - single owner
000002166 650__ $$aOccipital Lobe$$023130
000002166 650__ $$aBlindness$$015641
000002166 650__ $$aPhysical Stimulation$$024109
000002166 650__ $$aAttention$$015203
000002166 650__ $$aMagnetic Resonance Imaging$$021747
000002166 650__ $$aVisual Cortex$$027861
000002166 650__ $$aNeuroimaging$$039660
000002166 691__ $$aSchool of Medicine$$041369
000002166 692__ $$aDepartment of Behavioral Neuroscience$$041394
000002166 7001_ $$aWeaver, Kurt$$uOregon Health and Science University$$041354
000002166 8564_ $$9cfbc75cc-1db4-4388-a435-f7522e9e39e0$$s3019158$$uhttps://digitalcollections.ohsu.edu/record/2166/files/2895_etd.pdf$$ePublic$$2ea3152fd828871427f859c735e275d24$$31
000002166 901__ $$a<p>These documents are archival records. They are retained for historical reference only. </p><p><b>Need an accessible version? Use the ‘Get Accessible Copy’ link above.</b></p>
000002166 905__ $$a/rest/prod/bv/73/c0/59/bv73c059s
000002166 909CO $$ooai:digitalcollections.ohsu.edu:2166$$pstudent-work
000002166 956__ $$aGet Accessible Copy$$uhttps://ohsu.libwizard.com/f/requestaccessibledocument
000002166 980__ $$aTheses and Dissertations