000002168 001__ 2168 000002168 005__ 20260529131612.0 000002168 0247_ $$2DOI$$a10.6083/M4PV6HM6 000002168 037__ $$aETD 000002168 245__ $$aEffect of obesity on hepatic steatosis and fibrosis in a hepatitis-C infected population 000002168 260__ $$bOregon Health and Science University 000002168 269__ $$a2006 000002168 336__ $$aThesis 000002168 502__ $$bM.P.H. 000002168 520__ $$aObesity is a major public health concern linked to numerous comorbidities, including nonalcoholic fatty liver disease (NAFLD), which can progress to cirrhosis and liver failure. This study examined the association between obesity, chronic hepatitis C infection, and advanced hepatic steatosis and fibrosis in a community population. Advanced steatosis was independently associated with obesity, advanced fibrosis, and metabolic comorbidities. Advanced fibrosis was independently associated with steatosis, male gender, age, and site. These findings highlight the combined impact of obesity and hepatitis C on liver disease severity and underscore the importance of addressing metabolic risk factors in affected individuals. 000002168 540__ $$fCC BY 000002168 542__ $$fIn copyright - single owner 000002168 650__ $$aEpidemiology$$018518 000002168 650__ $$aFatty Liver$$018918 000002168 650__ $$aHepatitis C, Chronic$$031805 000002168 650__ $$aObesity$$023118 000002168 650__ $$aFibrosis$$019028 000002168 650__ $$aMale$$021762 000002168 650__ $$aLiver Failure$$029681 000002168 650__ $$aLiver Cirrhosis$$021584 000002168 650__ $$aNon-alcoholic Fatty Liver Disease$$040638 000002168 691__ $$aSchool of Medicine$$041369 000002168 692__ $$aDepartment of Public Health and Preventive Medicine$$041444 000002168 7001_ $$aHayman, Amanda$$uOregon Health and Science University$$041354 000002168 7201_ $$aZaman, Atif$$uOregon Health and Science University$$041354$$7Personal$$eAdvisor$$eChair 000002168 8564_ $$95fc08edf-1303-4357-a74f-fa62f611c828$$s3960261$$uhttps://digitalcollections.ohsu.edu/record/2168/files/2897_etd.pdf$$ePublic$$2dd9a9398a733a0379a6f26ef5d216cd9$$31 000002168 901__ $$a<p>These documents are archival records. They are retained for historical reference only. </p><p><b>Need an accessible version? Use the ‘Get Accessible Copy’ link above.</b></p> 000002168 905__ $$a/rest/prod/k0/69/87/61/k06987610 000002168 909CO $$ooai:digitalcollections.ohsu.edu:2168$$pstudent-work 000002168 956__ $$aGet Accessible Copy$$uhttps://ohsu.libwizard.com/f/requestaccessibledocument 000002168 980__ $$aTheses and Dissertations