000002171 001__ 2171 000002171 005__ 20260529130620.0 000002171 0247_ $$2DOI$$a10.6083/M49P2ZWH 000002171 037__ $$aETD 000002171 245__ $$aEvaluating the efficacy of an accelerated diphtheria, tetanus, and pertussis (DTaP) recommendation in southwestern Oregon counties during a pertussis outbreak in 2003 000002171 260__ $$bOregon Health and Science University 000002171 269__ $$a2006 000002171 336__ $$aThesis 000002171 502__ $$bM.P.H. 000002171 520__ $$aDespite widespread pertussis vaccination, outbreaks persist, posing significant risk to infants. This study evaluated whether an accelerated DTaP immunization schedule reduced dosing intervals during a 2003 Oregon outbreak. Using registry data from 5,036 children, mean intervals between doses were compared across counties with and without the recommendation and across time periods. Results showed significantly shorter post-recommendation intervals in counties adopting the accelerated schedule (p<0.0001), with no change in the comparison county. Reductions were consistent across clinic types after adjustment. Findings indicate that accelerated DTaP schedules are feasible and may support outbreak control efforts. 000002171 540__ $$fCC BY 000002171 542__ $$fIn copyright - single owner 000002171 650__ $$aWhooping Cough$$027975 000002171 650__ $$aDisease Outbreaks$$017933 000002171 650__ $$aTreatment Outcome$$029508 000002171 650__ $$aImmunization Schedule$$020674 000002171 650__ $$aDiphtheria-Tetanus-Pertussis Vaccine$$028599 000002171 650__ $$aTetanus$$026861 000002171 650__ $$aDiphtheria$$017902 000002171 650__ $$aInfant$$020774 000002171 650__ $$aChild$$016462 000002171 651__ $$aOregon$$041094 000002171 691__ $$aSchool of Medicine$$041369 000002171 692__ $$aDepartment of Public Health and Preventive Medicine$$041444 000002171 7001_ $$aWilson, Elisa$$uOregon Health and Science University$$041354 000002171 7201_ $$aGaudino, Jim$$uOregon Health and Science University$$041354$$7Personal$$eChair 000002171 8564_ $$98c75e989-f028-418b-818a-631f3869bdcd$$s3986257$$uhttps://digitalcollections.ohsu.edu/record/2171/files/2900_etd.pdf$$ePublic$$2a977f815f01a79c8bbc61fca599d71d7$$31 000002171 901__ $$a<p>These documents are archival records. They are retained for historical reference only. </p><p><b>Need an accessible version? Use the ‘Get Accessible Copy’ link above.</b></p> 000002171 905__ $$a/rest/prod/t1/48/fh/29/t148fh29q 000002171 909CO $$ooai:digitalcollections.ohsu.edu:2171$$pstudent-work 000002171 956__ $$aGet Accessible Copy$$uhttps://ohsu.libwizard.com/f/requestaccessibledocument 000002171 980__ $$aTheses and Dissertations