000002287 001__ 2287
000002287 005__ 20250424232722.0
000002287 0247_ $$2DOI$$a10.6083/M49Z9355
000002287 037__ $$aETD
000002287 245__ $$aA system for automated storage and analysis of single nucleotide polymorphism data
000002287 260__ $$bOregon Health and Science University
000002287 269__ $$a2005
000002287 336__ $$aThesis
000002287 502__ $$bM.B.I.
000002287 520__ $$aSingle nucleotide polymorphism genotyping provides a method of genotyping ideally suited to high throughput operations. However, individual variation at SNP loci presents little information regarding genotype or phenotype on a locus-by-locus basis. Computational inference methods provided solution for haplotype determination that is low cost, highly accurate, and suited to high throughput. The Oregon National Primate Research Center (ONPRC) has begun to utilize SNP genotyping but lacks an integrated solution for uploading to the Genome Resource Informatics Program Database and for subsequent analysis of that data. This thesis describes the design and implementation of a data upload and haplotype inference system for ONPRC.
000002287 540__ $$fCC BY
000002287 542__ $$fIn copyright - single owner
000002287 650__ $$aSequence Analysis$$029957
000002287 650__ $$aMedical Informatics$$021938
000002287 650__ $$aHaplotypes$$019848
000002287 650__ $$aPolymorphism, Single Nucleotide$$032570
000002287 650__ $$aDatabases, Genetic$$033839
000002287 650__ $$aInformatics$$036046
000002287 650__ $$aPhenotype$$023948
000002287 650__ $$aGenotype$$019486
000002287 691__ $$aSchool of Medicine$$041369
000002287 692__ $$aDepartment of Medical Informatics and Clinical Epidemiology$$041422
000002287 7001_ $$aWright, Hollis$$uOregon Health and Science University$$041354
000002287 8564_ $$987c73f80-7577-4b00-9cd4-a6ebe775b5d2$$s5086600$$uhttps://digitalcollections.ohsu.edu/record/2287/files/3016_etd.pdf$$ePublic$$2a3474df26d94da64512adbbfca1e911b$$31
000002287 905__ $$a/rest/prod/0k/22/5b/27/0k225b270
000002287 909CO $$ooai:digitalcollections.ohsu.edu:2287$$pstudent-work
000002287 980__ $$aBiomedical Informatics