000002373 001__ 2373 000002373 005__ 20250424232728.0 000002373 0247_ $$2DOI$$a10.6083/M4K35RX7 000002373 037__ $$aETD 000002373 245__ $$aAre there associations between paraesophageal hernia and collagen disorders or other diseases? -- a data mining approach 000002373 260__ $$bOregon Health and Science University 000002373 269__ $$a2003 000002373 336__ $$aThesis 000002373 502__ $$bM.S. 000002373 520__ $$aA hiatal hernia occurs when a portion of the stomach prolapses through the diaphragmatic esophageal hiatus. Even though it is believed that the major cause of hiatal hernias is loss of elasticity of supporting structures, the detailed mechanisms have not been fully studied. There are reports of a possible association between hiatal hernias and connective tissue weakness. Recently, studies of inguinal and incisional hernias have shown their connection to collagen matrix defects. The study reported here uses data mining techniques to explore the association between paraesophageal hernia and severe types of hiatal hernia and other disorders, including collagen. 000002373 540__ $$fCC BY 000002373 542__ $$fIn copyright - single owner 000002373 650__ $$aInformation Storage and Retrieval$$028998 000002373 650__ $$aMedical Informatics$$021938 000002373 650__ $$aCollagen Diseases$$016891 000002373 650__ $$aHernia, Hiatal$$020146 000002373 650__ $$aStomach$$026425 000002373 650__ $$aProlapse$$024657 000002373 650__ $$aCollagen$$016890 000002373 650__ $$aElasticity$$018266 000002373 650__ $$aConnective Tissue$$017025 000002373 691__ $$aSchool of Medicine$$041369 000002373 692__ $$aDepartment of Medical Informatics and Clinical Epidemiology$$041422 000002373 7001_ $$aYang, Jianji$$uOregon Health and Science University$$041354 000002373 7201_ $$aLogan, Judith$$uOregon Health and Science University$$041354$$7Personal$$eAdvisor 000002373 8564_ $$9bc68fd12-3f1d-4456-8b45-7f0051910c9b$$s4112132$$uhttps://digitalcollections.ohsu.edu/record/2373/files/3107_etd.pdf$$ePublic$$28d6848a4e8c213da0039654dd45c9e47$$31 000002373 905__ $$a/rest/prod/18/31/ck/15/1831ck152 000002373 909CO $$ooai:digitalcollections.ohsu.edu:2373$$pstudent-work 000002373 980__ $$aBiomedical Informatics