TY - THES AB - Analyzing and reporting data generated from cDNA microarray experiments is a challenging process. There are many potential sources of error that must be controlled to obtain valid and reproducible results from these experiments and estimate relative levels of gene expression. There is currently no proven best method of normalization or data processing for the analysis of microarray data. We wanted to find out whether we could generate a consistent and meaningful report of microarray gene expression results, correcting from systematic sources of variation, and ensure that the results are valid and reproducible for the genetics researcher. AD - Oregon Health and Science University AU - Rodland, Matthew DA - 2001 DO - 10.6083/M4Q52MWX DO - DOI ED - Dubay, Christopher ED - Advisor ID - 2482 KW - Software KW - Medical Informatics KW - Quality Control KW - DNA KW - Oligonucleotide Array Sequence Analysis KW - Gene Expression L1 - https://digitalcollections.ohsu.edu/record/2482/files/3223_etd.pdf L2 - https://digitalcollections.ohsu.edu/record/2482/files/3223_etd.pdf L4 - https://digitalcollections.ohsu.edu/record/2482/files/3223_etd.pdf LK - https://digitalcollections.ohsu.edu/record/2482/files/3223_etd.pdf N2 - Analyzing and reporting data generated from cDNA microarray experiments is a challenging process. There are many potential sources of error that must be controlled to obtain valid and reproducible results from these experiments and estimate relative levels of gene expression. There is currently no proven best method of normalization or data processing for the analysis of microarray data. We wanted to find out whether we could generate a consistent and meaningful report of microarray gene expression results, correcting from systematic sources of variation, and ensure that the results are valid and reproducible for the genetics researcher. PB - Oregon Health and Science University PY - 2001 T1 - Analysis and quality control of cDNA microarray data TI - Analysis and quality control of cDNA microarray data UR - https://digitalcollections.ohsu.edu/record/2482/files/3223_etd.pdf Y1 - 2001 ER -