TY  - GEN
AB  - Pathway research defines or refines our understanding of interactions between molecules within and between cells, primarily to identify molecular targets for disease therapies. Pathways interact to form networks. Pathways and networks should be understood as a concrete series of chemical reactions, but as abstract probabilistic models of molecular behavior. The past decade has witnessed exceptional growth in research involving the study of biological pathways and corresponding growth in bioinformatics tools to support it. Evolving concepts in the field are not always understood consistently, increasing the risk of misinterpreted or lost research. It is therefore imperative to bioinformaticians that possible areas of confusion be identified and clarified.
AD  - Oregon Health and Science University
AU  - Ames, Michael
DA  - 2010-05-01
DO  - 10.6083/M41V5CQM
DO  - DOI
ED  - McWeeney, Shannon
ED  - Advisor
ID  - 2761
KW  - Models, Statistical
KW  - Computational Biology
L1  - https://digitalcollections.ohsu.edu/record/2761/files/3527_etd.pdf
L2  - https://digitalcollections.ohsu.edu/record/2761/files/3527_etd.pdf
L4  - https://digitalcollections.ohsu.edu/record/2761/files/3527_etd.pdf
LK  - https://digitalcollections.ohsu.edu/record/2761/files/3527_etd.pdf
N2  - Pathway research defines or refines our understanding of interactions between molecules within and between cells, primarily to identify molecular targets for disease therapies. Pathways interact to form networks. Pathways and networks should be understood as a concrete series of chemical reactions, but as abstract probabilistic models of molecular behavior. The past decade has witnessed exceptional growth in research involving the study of biological pathways and corresponding growth in bioinformatics tools to support it. Evolving concepts in the field are not always understood consistently, increasing the risk of misinterpreted or lost research. It is therefore imperative to bioinformaticians that possible areas of confusion be identified and clarified.
PB  - Oregon Health and Science University
PY  - 2010-05-01
T1  - Current trends and terminology in systems biology and pathway research: a conceptual roadmap
TI  - Current trends and terminology in systems biology and pathway research: a conceptual roadmap
UR  - https://digitalcollections.ohsu.edu/record/2761/files/3527_etd.pdf
Y1  - 2010-05-01
ER  -