000002829 001__ 2829 000002829 005__ 20251031140438.0 000002829 0247_ $$2DOI$$a10.6083/M4445K62 000002829 037__ $$aETD 000002829 245__ $$aStructure and function of the GluN1-GluN2B NMDA receptor 000002829 260__ $$bOregon Health and Science University 000002829 269__ $$a2015 000002829 336__ $$aDissertation 000002829 502__ $$bPh.D. 000002829 502__ $$gNeuroscience 000002829 520__ $$aNeurons, information-processing units of the human brain, are polarized cells that have a soma, tentacle-like dendrites and a typically tubular axon. For information transfer, the axon of a neuron create contacts with the soma or dendrites of another neuron. In the mammalian nervous system, most neurons communicate through chemical synapses. I am interested in understanding the molecular mechanism of chemical synaptic transmission in excitatory neurons or, more specifically, in glutamatergic neurons. 000002829 540__ $$fCC BY 000002829 542__ $$fIn copyright - single owner 000002829 650__ $$aSynapses$$026704 000002829 650__ $$aReceptors, Glutamate$$029996 000002829 650__ $$aCrystallography, X-Ray$$030746 000002829 650__ $$aReceptors, N-Methyl-D-Aspartate$$028954 000002829 691__ $$aSchool of Medicine$$041369 000002829 692__ $$aVollum Institute$$041509 000002829 7001_ $$aLee, Chia-Hsueh$$uOregon Health and Science University$$041354 000002829 8564_ $$9a1b8530e-7b0e-426d-9160-2b495033a2ff$$s5901207$$uhttps://digitalcollections.ohsu.edu/record/2829/files/3597_etd.pdf$$ePublic$$27706518fd6287d0a499a6a8acd1674f1$$31 000002829 905__ $$a/rest/prod/g4/45/cd/31/g445cd317 000002829 909CO $$ooai:digitalcollections.ohsu.edu:2829$$pstudent-work 000002829 980__ $$aTheses and Dissertations