000002849 001__ 2849
000002849 005__ 20251113130707.0
000002849 0247_ $$2DOI$$a10.6083/M40Z722V
000002849 037__ $$aETD
000002849 245__ $$aCombined oral contraceptive pills in obese women: effectiveness, safety, and the role of biomarkers in risk assessment
000002849 269__ $$a2015
000002849 336__ $$aThesis
000002849 502__ $$bM.P.H.
000002849 520__ $$aObesity    alters    pharmacokinetics    (PK)    of    contraceptive    hormones    and    has    the     potential    to    contribute    to    contraceptive    failure.        It    is    also    a    risk    factor    for    venous     thromboembolism    (VTE).        The    current    project    aims    to    study    the    influence    of    the    binding     protein    sex    hormone    binding    globulin    (SHBG)    on    levonorgestrel    (LNG)    pharmacokinetics,     and    to    study    changes    in    anticoagulation    parameters    protein    C    activity    and    free    protein    S,    in     a    population    of    obese    women    initiating    combined    oral    contraceptive    pills    (COCs).
000002849 540__ $$fCC BY
000002849 542__ $$fIn copyright - single owner
000002849 650__ $$aPharmacokinetics$$023908
000002849 650__ $$aThromboembolism$$027030
000002849 650__ $$aObesity$$023118
000002849 650__ $$aContraceptives, Oral, Combined$$017064
000002849 650__ $$aBiomarkers$$028395
000002849 691__ $$aSchool of Medicine$$041369
000002849 692__ $$aDepartment of Public Health and Preventive Medicine$$041444
000002849 7001_ $$aSimmons, Katharine$$uOregon Health and Science University$$041354
000002849 8564_ $$9b04dd82d-1451-4bbb-9dbb-8ea48cd34779$$s4373649$$uhttps://digitalcollections.ohsu.edu/record/2849/files/3617_etd.pdf$$ePublic$$20ba3670633a521bdf6a315efcf746451$$31
000002849 905__ $$a/rest/prod/fn/10/6z/30/fn106z30d
000002849 909CO $$ooai:digitalcollections.ohsu.edu:2849$$pstudent-work
000002849 980__ $$aTheses and Dissertations