000002991 001__ 2991
000002991 005__ 20250424232808.0
000002991 0247_ $$2DOI$$a10.6083/M41J98T4
000002991 037__ $$aETD
000002991 245__ $$aNew approaches for enhancing the selectivity and activity of thyroid hormone analogs
000002991 269__ $$a2016-06-01
000002991 336__ $$aDissertation
000002991 502__ $$bPh.D.
000002991 520__ $$aThyroid hormones control a wide range of physiological processes in all  known vertebrates. These actions are mediated by two different receptor  subtypes that have heterogeneous distribution in tissues. While the endogenous  hormone does not distinguish between the two subtypes, synthetic ligands have  been made that will preferentially activate one subtype over the other in vitro.
000002991 542__ $$fIn copyright - single owner
000002991 650__ $$aBlood-Brain Barrier$$015687
000002991 650__ $$aPharmacokinetics$$023908
000002991 650__ $$aChemistry, Pharmaceutical$$016443
000002991 650__ $$aThyroid Hormones$$027070
000002991 691__ $$aSchool of Medicine$$041369
000002991 692__ $$aDepartment of Physiology and Pharmacology$$041442
000002991 7001_ $$aDevereaux, Jordan$$uOregon Health and Science University$$041354$$10000-0002-8542-7411
000002991 7201_ $$aScanlan, Thomas$$uOregon Health and Science University$$041354$$7Personal$$eAdvisor
000002991 8564_ $$994ebc53d-8d32-4da8-8a71-b3ed4ddc1e20$$s40708424$$uhttps://digitalcollections.ohsu.edu/record/2991/files/3792_etd.pdf$$ePublic$$2758a97df53a6e5ac46ca2e8a7ea134d5$$31
000002991 905__ $$a/rest/prod/bn/99/97/04/bn999704x
000002991 909CO $$ooai:digitalcollections.ohsu.edu:2991$$pstudent-work
000002991 980__ $$aTheses and Dissertations