TY  - GEN
AB  - According to the American Diabetes Association, approximately 30 million Americans were diagnosed with diabetes as of 2012, representing over ten percent of the population. The International Diabetes Federation predicts that this number will rise from 415 million to 642 million worldwide by 2040. Both genetic and environmental factors increase the risk of Type 2 diabetes, with epigenetic factors like DNA methylation and histone modification also playing a role. I participated in an ongoing study analyzing insulin resistance in human adipocytes, aiming to explore genetic variants and how single nucleotide polymorphisms (SNPs) differ between insulin-resistant and insulin-sensitive individuals.
AD  - Oregon Health and Science University
AU  - Choi, Ashley
DA  - 2016-09-01
DO  - 10.6083/M48051PK
DO  - DOI
ED  - Wu, Guanming
ED  - Advisor
ID  - 3022
KW  - Diabetes Mellitus, Type 2
KW  - Insulin Resistance
KW  - Polymorphism, Single Nucleotide
KW  - DNA Methylation
KW  - Histone Code
KW  - Adipocytes
KW  - Epigenesis, Genetic
L1  - https://digitalcollections.ohsu.edu/record/3022/files/3829_etd.pdf
L2  - https://digitalcollections.ohsu.edu/record/3022/files/3829_etd.pdf
L4  - https://digitalcollections.ohsu.edu/record/3022/files/3829_etd.pdf
LK  - https://digitalcollections.ohsu.edu/record/3022/files/3829_etd.pdf
N2  - According to the American Diabetes Association, approximately 30 million Americans were diagnosed with diabetes as of 2012, representing over ten percent of the population. The International Diabetes Federation predicts that this number will rise from 415 million to 642 million worldwide by 2040. Both genetic and environmental factors increase the risk of Type 2 diabetes, with epigenetic factors like DNA methylation and histone modification also playing a role. I participated in an ongoing study analyzing insulin resistance in human adipocytes, aiming to explore genetic variants and how single nucleotide polymorphisms (SNPs) differ between insulin-resistant and insulin-sensitive individuals.
PB  - Oregon Health and Science University
PY  - 2016-09-01
T1  - Preliminary genome-wide association analysis of insulin resistance in Americans
TI  - Preliminary genome-wide association analysis of insulin resistance in Americans
UR  - https://digitalcollections.ohsu.edu/record/3022/files/3829_etd.pdf
Y1  - 2016-09-01
ER  -