TY  - GEN
AB  - How are complex, learned behaviors—like speech and singing—encoded in our genes, and how did they evolve? Human speech depends on our ability to learn and control vocalizations, a process not well understood at the molecular level. This ability is rare in the animal kingdom and is absent in our closest primate relatives and common laboratory rodents.  To explore the neural and genetic bases of vocal learning, I conducted comparative experiments with over 50 avian species. This research involved developing new computational analysis pipelines and adapting lab practices for field studies, significantly enhancing our understanding of gene expression and regulation in birds. Ultimately, these findings investigate three potential mechanisms for the evolution of a brain circuit that controls complex sensorimotor tasks.
AD  - Oregon Health and Science University
AU  - Wirthlin, Morgan
DA  - 2016-09-01
DO  - 10.6083/M40G3J80
DO  - DOI
ED  - Mello, Claudio
ED  - Carbone, Lucia
ED  - David, Stephen
ED  - Raber, Jacob
ED  - Brigande, John
ED  - Advisor
ED  - Mentor
ED  - Committee chair
ED  - Committee member
ED  - Committee member
ED  - Committee member
ID  - 3023
KW  - Gene Expression
KW  - Speech
L1  - https://digitalcollections.ohsu.edu/record/3023/files/3831_etd.pdf
L2  - https://digitalcollections.ohsu.edu/record/3023/files/3831_etd.pdf
L4  - https://digitalcollections.ohsu.edu/record/3023/files/3831_etd.pdf
LK  - https://digitalcollections.ohsu.edu/record/3023/files/3831_etd.pdf
N2  - How are complex, learned behaviors—like speech and singing—encoded in our genes, and how did they evolve? Human speech depends on our ability to learn and control vocalizations, a process not well understood at the molecular level. This ability is rare in the animal kingdom and is absent in our closest primate relatives and common laboratory rodents.  To explore the neural and genetic bases of vocal learning, I conducted comparative experiments with over 50 avian species. This research involved developing new computational analysis pipelines and adapting lab practices for field studies, significantly enhancing our understanding of gene expression and regulation in birds. Ultimately, these findings investigate three potential mechanisms for the evolution of a brain circuit that controls complex sensorimotor tasks.
PB  - Oregon Health and Science University
PY  - 2016-09-01
T1  - Evolutionary neurogenomic approaches provide insight into the molecular basis of vocal learning
TI  - Evolutionary neurogenomic approaches provide insight into the molecular basis of vocal learning
UR  - https://digitalcollections.ohsu.edu/record/3023/files/3831_etd.pdf
Y1  - 2016-09-01
ER  -