000003044 001__ 3044 000003044 005__ 20250424232812.0 000003044 0247_ $$2DOI$$a10.6083/M4HH6J5S 000003044 037__ $$aETD 000003044 245__ $$aExpression variations associated with influenza infection severity in humans and mice 000003044 260__ $$bOregon Health and Science University 000003044 269__ $$a2017 000003044 336__ $$aThesis 000003044 502__ $$bM.S. 000003044 520__ $$aInfluenza is a disease that is estimated by the World Health Organization (WHO) to affect 5-10% of adults and 20-30% of children each year. Using this collaborative cross and available human data, this project sought to answer the following question: what genes and pathways are differentially expressed during mild and severe influenza infections in the collaborative cross mouse model, and do these mirror the differential expression seen in existing human influenza severity data? 000003044 540__ $$fCC BY 000003044 542__ $$fIn copyright - single owner 000003044 650__ $$aInformatics$$036046 000003044 650__ $$aMice$$036842 000003044 650__ $$aInfluenza, Human$$020802 000003044 691__ $$aSchool of Medicine$$041369 000003044 7001_ $$aHunter, Jeffrey$$uOregon Health and Science University$$041354$$10000-0002-1565-3579 000003044 7201_ $$aMcWeeney, Shannon$$uOregon Health and Science University$$041354$$7Personal$$eAdvisor 000003044 8564_ $$9b3e2cf55-d1c6-475d-8d5c-e54ef276219d$$s765438$$uhttps://digitalcollections.ohsu.edu/record/3044/files/3874_etd.pdf$$ePublic$$2554ad88b3649b207d98b486cebc7520d$$31 000003044 905__ $$a/rest/prod/zp/38/wc/90/zp38wc90p 000003044 909CO $$ooai:digitalcollections.ohsu.edu:3044$$pstudent-work 000003044 980__ $$aBiomedical Informatics