000003045 001__ 3045 000003045 005__ 20231208142813.0 000003045 0247_ $$2DOI$$a10.6083/M4CR5SF2 000003045 037__ $$aETD 000003045 245__ $$aReliability issues in imaging genetics 000003045 269__ $$a2017 000003045 336__ $$aCapstone 000003045 502__ $$bM.B.I. 000003045 520__ $$aIn behavioral neuroscience, questions of development and function are often pursued using either genetic or imaging approaches. The genetics of behavior has been studied in order to shed light on the processes that guide human psychological development. The underlying genetic basis for behavior has long been the subject of debate, but it has been accepted that genes play a role in both behavioral tendencies and susceptibility to disorders of the brain. In this paper, I will address issues of reliability facing the field of imaging genetics. Reliability (measurements and metrics of consistency or accuracy), in this context, is a time-sensitive matter requiring both excellent communication and sensitivity. I will examine the current approaches used to address these issues in each field separately, with examples from the large consortia that demonstrate both best practices and the computational expertise required. 000003045 540__ $$fCC BY 000003045 542__ $$fIn copyright - single owner 000003045 650__ $$aResearch$$025336 000003045 650__ $$aNeuroimaging$$039660 000003045 650__ $$aPsychopathology$$024852 000003045 650__ $$aReproducibility of Results$$028215 000003045 650__ $$aGenotype$$019486 000003045 6531_ $$aendophenotype 000003045 691__ $$aSchool of Medicine$$041369 000003045 7001_ $$aEriksson, Annika$$uOregon Health and Science University$$041354 000003045 8564_ $$99d6f931b-9c5e-481f-8155-39afc5b1f076$$s490609$$uhttps://digitalcollections.ohsu.edu/record/3045/files/3875_etd.pdf 000003045 905__ $$a/rest/prod/x6/33/f1/30/x633f1307 000003045 909CO $$ooai:digitalcollections.ohsu.edu:3045$$pstudent-work 000003045 980__ $$aTheses and Dissertations