000003060 001__ 3060 000003060 005__ 20251009115619.0 000003060 0247_ $$2DOI$$a10.6083/M43F4P6Q 000003060 037__ $$aETD 000003060 245__ $$aThe subjective effects of ethanol in Rhesus monkeys: characterizing the role of the nucleus accumbens using chemogenetics 000003060 260__ $$bOregon Health and Science University 000003060 269__ $$a2018 000003060 336__ $$aDissertation 000003060 502__ $$bPh.D. 000003060 502__ $$gBehavioral & Systems Neuroscience 000003060 520__ $$aAlcoholism is a chronic, progressive disorder often characterized by patterns of binge drinking that leads to detrimental health consequences and a great economic burden on society. Alcohol (ethanol) is known to produce interoceptive (i.e., internally generated) effects that can be recognized and described by the user. Thus, the first aim of this dissertation was to characterize the pharmacological basis of ethanol discrimination in rhesus macaques. 000003060 540__ $$fCC BY 000003060 542__ $$fIn copyright - single owner 000003060 650__ $$aEthanol$$014406 000003060 650__ $$aNucleus Accumbens$$023067 000003060 650__ $$aReceptors, GABA-A$$025198 000003060 650__ $$aAlcoholism$$014412 000003060 650__ $$aMacaca mulatta$$021724 000003060 650__ $$aBinge Drinking$$040232 000003060 6531_ $$adrug discrimination 000003060 6531_ $$achemogenetics 000003060 691__ $$aSchool of Medicine$$041369 000003060 692__ $$aDepartment of Behavioral Neuroscience$$041394 000003060 7001_ $$aAllen, Daicia$$uOregon Health and Science University$$041354$$10000-0002-4767-1237 000003060 7201_ $$aGrant, Kathleen$$uOregon Health and Science University$$041354$$7Personal$$eAdvisor$$eMentor 000003060 8564_ $$935165d74-2aeb-4f60-80b1-cc7e0b8ed58a$$s29055322$$uhttps://digitalcollections.ohsu.edu/record/3060/files/3993_etd.pdf$$ePublic$$2d42579e1ecb87a5ccea7f043c26cddc1$$31 000003060 905__ $$a/rest/prod/dr/26/xx/58/dr26xx58m 000003060 909CO $$ooai:digitalcollections.ohsu.edu:3060$$pstudent-work 000003060 980__ $$aTheses and Dissertations