000003070 001__ 3070 000003070 005__ 20251010131300.0 000003070 0247_ $$2DOI$$a10.6083/M470810F 000003070 037__ $$aETD 000003070 245__ $$aMicrobiome community inference in low microbial biomass environments 000003070 269__ $$a2018 000003070 336__ $$aThesis 000003070 502__ $$bM.S. 000003070 502__ $$gBioinformatics & Computational Biomedicine 000003070 520__ $$aMicrobiome community compositon is an important factor in human health, and while most microbiome research to date has focused on high microbial biomass communites, low biomass communites, such as found in the urinary tract, are also of medical importance. The relatve scarcity of microbes in low biomass communites makes an accurate determinaton of community compositon challenging, since contaminaton and technical noise may confound the true community signal when biomass is very low. However, the impact of these noise sources on microbial community inference is not well studied. 000003070 540__ $$fCC BY 000003070 542__ $$fIn copyright - single owner 000003070 650__ $$aBiomass$$030882 000003070 650__ $$aMicrobiota$$040384 000003070 650__ $$aCluster Analysis$$028809 000003070 650__ $$aRNA, Ribosomal, 16S$$025549 000003070 691__ $$aSchool of Medicine$$041369 000003070 692__ $$aDepartment of Medical Informatics and Clinical Epidemiology$$041422 000003070 7001_ $$aCaruso, Vincent$$uOregon Health and Science University$$041354$$10000-0002-8738-2552 000003070 7201_ $$aKarstens, Lisa$$uOregon Health and Science University$$041354$$7Personal$$eAdvisor 000003070 8564_ $$905e07f0e-80a2-4b22-8e37-ba3a1c4443d9$$s3664256$$uhttps://digitalcollections.ohsu.edu/record/3070/files/4003_etd.pdf$$ePublic$$284da8b307d1d18b18e230001b1d55c6f$$31 000003070 905__ $$a/rest/prod/sb/39/78/56/sb397856r 000003070 909CO $$ooai:digitalcollections.ohsu.edu:3070$$pstudent-work 000003070 980__ $$aTheses and Dissertations