@article{ETD,
      recid = {3073},
      author = {Urdang, Zachary},
      title = {Toll-like receptor four and neutrophil contributions to  endotoxemia - enhanced aminoglycoside ototoxicity},
      publisher = {Oregon Health and Science University},
      school = {Ph.D.},
      address = {2018},
      number = {ETD},
      abstract = {Drug-Induced Ototoxicity is a widespread global problem  occurring as a side effect of otherwise effective therapies  for conditions such as bacterial sepsis (aminoglycosides)  and cancers (platinum-based chemotherapy). It is becoming  clear that having the conditions requiring these drugs  itself puts the patient at increased risk for acquiring  life-long hearing loss. This apparent clinical paradox  places the provider in difficult position where treating  the life-threatening condition will most likely result in  poor hearing outcomes. Since these ototoxic therapies are  both life-saving and economically viable, understanding the  mechanisms of hearing loss and developing effective  strategies to preserve hearing during treatment for  life-threatening illness has the potential to greatly  enhance the quality of life in vulnerable patient  populations.},
      url = {http://digitalcollections.ohsu.edu/record/3073},
      doi = {https://doi.org/10.6083/M4N29WH9},
}