TY  - GEN
AB  - What properties, at the level of individual molecules, are responsible for allowing the adaptive immune system to differentiate cancerous cells from surrounding healthy tissue? This question is the bedrock of tumor immunology, for without some method of differentiation it would be impossible for immunity to recognize and kill tumor cells without simultaneously damaging normal organ systems. The primary hypothesis underlying this document is that an improved ability to measure and monitor antigen-specific adaptive immunity will lead to improved outcomes for patients with cancer.
AD  - Oregon Health and Science University
AU  - Hulett, Tyler
DA  - 2018-06-01
DO  - 10.6083/45bn-ra31
DO  - DOI
ED  - Fox, Bernard A.
ED  - David, Larry
ED  - Gough, Michael
ED  - Spellman, Paul
ED  - McCarty, Owen
ED  - Lind, Evan
ED  - Advisor
ED  - Chair
ED  - Committee member
ED  - Committee member
ED  - Committee member
ED  - Committee member
ID  - 3079
KW  - Neoplasms
KW  - Antigens
KW  - Immune System
KW  - Adaptive Immunity
L1  - https://digitalcollections.ohsu.edu/record/3079/files/4014_etd.pdf
L2  - https://digitalcollections.ohsu.edu/record/3079/files/4014_etd.pdf
L4  - https://digitalcollections.ohsu.edu/record/3079/files/4014_etd.pdf
LK  - https://digitalcollections.ohsu.edu/record/3079/files/4014_etd.pdf
N2  - What properties, at the level of individual molecules, are responsible for allowing the adaptive immune system to differentiate cancerous cells from surrounding healthy tissue? This question is the bedrock of tumor immunology, for without some method of differentiation it would be impossible for immunity to recognize and kill tumor cells without simultaneously damaging normal organ systems. The primary hypothesis underlying this document is that an improved ability to measure and monitor antigen-specific adaptive immunity will lead to improved outcomes for patients with cancer.
PY  - 2018-06-01
T1  - Coordinated IgG antibody and CD8+ T cell recognition of tumor antigens
TI  - Coordinated IgG antibody and CD8+ T cell recognition of tumor antigens
UR  - https://digitalcollections.ohsu.edu/record/3079/files/4014_etd.pdf
Y1  - 2018-06-01
ER  -