TY - GEN AB - Atopic dermatitis is a chronic relapsing inflammatory disease of the skin characterized by chronic itch. Eosinophils, and eosinophils products, are present in the skin in patients with atopic dermatitis, though what role they play in mediating itch and inflammation in the skin is unknown. Potential mechanisms by which eosinophils cause itch and inflammation in the skin were studied in this dissertation. AD - Oregon Health and Science University AU - Roth-Carter, Quinn DA - 2018-06-01 DO - 10.6083/5ZNAE8 DO - DOI ED - Giraud, George ED - Kulesz-Martin, Molly ED - Smith, Stephen ED - Leachman, Sancy ED - Cohen, Michael ED - Jacoby, David ED - Committee chair ED - Advisor ED - Committee member ED - Committee member ED - Committee member ED - Mentor ID - 3093 KW - Pruritus KW - Dermatitis, Atopic KW - Eosinophil Peroxidase KW - Skin KW - Inflammation KW - Eosinophils L1 - https://digitalcollections.ohsu.edu/record/3093/files/4050_etd.pdf L2 - https://digitalcollections.ohsu.edu/record/3093/files/4050_etd.pdf L4 - https://digitalcollections.ohsu.edu/record/3093/files/4050_etd.pdf LK - https://digitalcollections.ohsu.edu/record/3093/files/4050_etd.pdf N2 - Atopic dermatitis is a chronic relapsing inflammatory disease of the skin characterized by chronic itch. Eosinophils, and eosinophils products, are present in the skin in patients with atopic dermatitis, though what role they play in mediating itch and inflammation in the skin is unknown. Potential mechanisms by which eosinophils cause itch and inflammation in the skin were studied in this dissertation. PB - Oregon Health and Science University PY - 2018-06-01 T1 - Eosinophils mediate inflammation in the skin through the activity of eosinophil peroxidase TI - Eosinophils mediate inflammation in the skin through the activity of eosinophil peroxidase UR - https://digitalcollections.ohsu.edu/record/3093/files/4050_etd.pdf Y1 - 2018-06-01 ER -