TY  - GEN
AB  - Asthma is characterized by airway hyperreactivity, an abnormal tendency for airways to constrict. Maternal asthma increases the risk of childhood asthma more than paternal disease, suggesting intrauterine exposures contribute to airway hyperreactivity. As airway hyperreactivity seldom returns to the normal range despite intensive treatment, this suggests that structural alterations with in  utero origins impair lung function lifelong. I hypothesized that airway hyperreactivity in offspring born to mothers with asthma is established during development and results from increased lung sensory innervation.
AD  - Oregon Health and Science University
AU  - Lebold, Katherine
DA  - 2018-05-01
DO  - 10.6083/5C2L2I
DO  - DOI
ED  - Jacoby, David
ED  - Marks, Daniel
ED  - Fryer, Allison
ED  - Giraud, George
ED  - Thornburg, Kent
ED  - Advisor
ED  - Committee member
ED  - Committee chair
ED  - Committee member
ID  - 3110
KW  - Lung
KW  - Asthma
L1  - https://digitalcollections.ohsu.edu/record/3110/files/4071_etd.pdf
L2  - https://digitalcollections.ohsu.edu/record/3110/files/4071_etd.pdf
L4  - https://digitalcollections.ohsu.edu/record/3110/files/4071_etd.pdf
LK  - https://digitalcollections.ohsu.edu/record/3110/files/4071_etd.pdf
N2  - Asthma is characterized by airway hyperreactivity, an abnormal tendency for airways to constrict. Maternal asthma increases the risk of childhood asthma more than paternal disease, suggesting intrauterine exposures contribute to airway hyperreactivity. As airway hyperreactivity seldom returns to the normal range despite intensive treatment, this suggests that structural alterations with in  utero origins impair lung function lifelong. I hypothesized that airway hyperreactivity in offspring born to mothers with asthma is established during development and results from increased lung sensory innervation.
PB  - Oregon Health and Science University
PY  - 2018-05-01
T1  - Pre and postnatal determinants of airway hyperreactivity
TI  - Pre and postnatal determinants of airway hyperreactivity
UR  - https://digitalcollections.ohsu.edu/record/3110/files/4071_etd.pdf
Y1  - 2018-05-01
ER  -