000003130 001__ 3130
000003130 005__ 20250424232817.0
000003130 0247_ $$2DOI$$a10.6083/0XHVMK
000003130 037__ $$aETD
000003130 245__ $$aThe role of personal and familial alcohol misuse in temporal decision making and white matter microstructural development during adolescence
000003130 260__ $$bOregon Health and Science University
000003130 269__ $$a2018-09-01
000003130 336__ $$aDissertation
000003130 502__ $$bPh.D.
000003130 520__ $$aAdolescence is a time of significant neurobiological development and is characterized by many social, environmental, and behavioral changes. It is also a period of heightened risk-taking behavior, including the decision to drink. One significant predictor of future alcohol misuse is a family history of alcoholism. In adolescence, both personal and familial alcohol misuse have been shown to be associated with structural alterations in the brain, as well as greater impulsive choice – a temporal facet of decision making. In this dissertation, a monetary gain discounting paradigm was used to investigate the interactive role that both personal and familial alcohol misuse play in the longitudinal development of impulsive choice across adolescence.
000003130 542__ $$fIn copyright - single owner
000003130 650__ $$aDecision Making$$017417
000003130 650__ $$aRisk-Taking$$025524
000003130 650__ $$aEthanol$$014406
000003130 650__ $$aBrain$$015788
000003130 650__ $$aWhite Matter$$040768
000003130 650__ $$aAlcoholism$$014412
000003130 650__ $$aAdolescent$$014285
000003130 691__ $$aSchool of Medicine$$041369
000003130 692__ $$aDepartment of Behavioral Neuroscience$$041394
000003130 7001_ $$aJones, Scott$$uOregon Health and Science University$$041354
000003130 7201_ $$aNagel, Bonnie$$uOregon Health and Science University$$041354$$7Personal$$eAdvisor
000003130 8564_ $$9054c138d-ea1f-4c70-9929-09452e57a517$$s2012418$$uhttps://digitalcollections.ohsu.edu/record/3130/files/4094_etd.pdf$$ePublic$$2062101b30aba72fec75f1cd669493c34$$31
000003130 905__ $$a/rest/prod/gf/06/g2/89/gf06g289f
000003130 909CO $$ooai:digitalcollections.ohsu.edu:3130$$pstudent-work
000003130 980__ $$aTheses and Dissertations