TY  - GEN
AB  - Despite incredible advances in cancer treatment in recent years, precision  oncology faces many ongoing challenges in selecting the best treatment for each  patient. First, we have yet to untangle the mechanisms by which many of our drugs  act, especially with regards to the targets (receptors) to which they bind in the  human body. To this aim we present the Cancer Targetome, which collects drug- target interactions for FDA-approved cancer drugs and proposes an evidence  framework for the supporting  information  accompanying  each  drug-target  interaction.
AD  - Oregon Health and Science University
AU  - Blucher, Aurora
DA  - 2018
DO  - 10.6083/K5WJ1C
DO  - DOI
ED  - Wu, Guanming
ED  - McWeeney, Shannon
ED  - Mentor
ED  - Advisor
ED  - Mentor
ID  - 3132
KW  - Medical Oncology
KW  - Neoplasms
KW  - cancer
L1  - https://digitalcollections.ohsu.edu/record/3132/files/4096_etd.pdf
L2  - https://digitalcollections.ohsu.edu/record/3132/files/4096_etd.pdf
L4  - https://digitalcollections.ohsu.edu/record/3132/files/4096_etd.pdf
LK  - https://digitalcollections.ohsu.edu/record/3132/files/4096_etd.pdf
N2  - Despite incredible advances in cancer treatment in recent years, precision  oncology faces many ongoing challenges in selecting the best treatment for each  patient. First, we have yet to untangle the mechanisms by which many of our drugs  act, especially with regards to the targets (receptors) to which they bind in the  human body. To this aim we present the Cancer Targetome, which collects drug- target interactions for FDA-approved cancer drugs and proposes an evidence  framework for the supporting  information  accompanying  each  drug-target  interaction.
PB  - Oregon Health and Science University
PY  - 2018
T1  - The cancer targetome and its application to a pathway perspective on targeted therapy response in acute myeloid leukemia
TI  - The cancer targetome and its application to a pathway perspective on targeted therapy response in acute myeloid leukemia
UR  - https://digitalcollections.ohsu.edu/record/3132/files/4096_etd.pdf
Y1  - 2018
ER  -