000003134 001__ 3134
000003134 005__ 20231214170707.0
000003134 0247_ $$2DOI$$a10.6083/2RAOB3
000003134 037__ $$aETD
000003134 245__ $$aImpact of exercise on sleep and glycemic outcomes in adults with type 1 diabetes: towards predictive models and decision support systems
000003134 260__ $$bOregon Health and Science University
000003134 269__ $$a2018
000003134 336__ $$aDissertation
000003134 502__ $$bPh.D.
000003134 502__ $$gBiomedical Engineering
000003134 520__ $$aType 1 diabetes (T1D) is an autoimmune disease characterized by the destruction of pancreatic β cells and culminating with absolute insulin deficiency. Intensive insulin therapy is the standard of care for individuals with T1D, but attaining optimal glycemic control is extremely onerous and requires multiple daily insulin injections or continuous subcutaneous insulin infusion by an insulin pump, complemented by frequent monitoring of blood glucose (BG). Besides the usual barriers (i.e. lack of time/space, low energy, work etc.) individuals with T1D list fear of hypoglycemia as an important barrier to engage in PA. During PA there is an increased risk of hypoglycemia and pronounced glycemic imbalance. Moreover, exercise me- diated hypoglycemic risk is amplified not only during the bout of exercise but also for many hours after. The objective of this dissertation is to both understand the glycemic challenges associated with physical activity and develop model-based decision support systems to assist these individuals during and after PA.
000003134 540__ $$fCC BY
000003134 542__ $$fIn copyright - single owner
000003134 650__ $$aGlycemic Control$$013452
000003134 650__ $$aAutoimmune Diseases$$015237
000003134 650__ $$aGlycemic Control$$013452
000003134 650__ $$aExercise$$028419
000003134 691__ $$aSchool of Medicine$$041369
000003134 692__ $$aDepartment of Biomedical Engineering$$041397
000003134 7001_ $$aReddy, Ravi K.K.$$uOregon Health and Science University$$041354$$10000-0001-9612-1314
000003134 8564_ $$95e1ab8fe-6a4c-4be0-b7dd-f197f1e1e9ed$$s6848082$$uhttps://digitalcollections.ohsu.edu/record/3134/files/4098_etd.pdf
000003134 905__ $$a/rest/prod/98/80/vr/26/9880vr26p
000003134 909CO $$ooai:digitalcollections.ohsu.edu:3134$$pstudent-work
000003134 980__ $$aTheses and Dissertations