TY - GEN AB - Biological sensory systems encode environmental information through large populations of receptors whose activity reaches the brain as parallel spike trains. Understanding how these signals are transformed and which stimulus features are most meaningful to the organism is a central challenge in neuroscience. This dissertation illustrates a comprehensive, data‑driven framework for analyzing relationships between stimuli and their neural representations, complementing traditional hypothesis‑driven approaches. Stimulus sets and neural responses are characterized either categorically or within continuous similarity spaces, and analytical methods are adapted or developed to quantify input–output relationships. Across the datasets examined, stimulus timing consistently emerged as a key feature governing neural encoding. AD - Oregon Health and Science University AU - Iancu, Ovidiu DA - 2008 DO - 10.6083/M4610X8S DO - DOI ED - Roberts, Patrick ED - Advisor ID - 338 KW - Nervous System KW - Information Storage and Retrieval KW - image segmentation KW - neural stimulation KW - biophysical model KW - response attenuation L1 - https://digitalcollections.ohsu.edu/record/338/files/339_etd.pdf L2 - https://digitalcollections.ohsu.edu/record/338/files/339_etd.pdf L4 - https://digitalcollections.ohsu.edu/record/338/files/339_etd.pdf LK - https://digitalcollections.ohsu.edu/record/338/files/339_etd.pdf N2 - Biological sensory systems encode environmental information through large populations of receptors whose activity reaches the brain as parallel spike trains. Understanding how these signals are transformed and which stimulus features are most meaningful to the organism is a central challenge in neuroscience. This dissertation illustrates a comprehensive, data‑driven framework for analyzing relationships between stimuli and their neural representations, complementing traditional hypothesis‑driven approaches. Stimulus sets and neural responses are characterized either categorically or within continuous similarity spaces, and analytical methods are adapted or developed to quantify input–output relationships. Across the datasets examined, stimulus timing consistently emerged as a key feature governing neural encoding. PB - Oregon Health and Science University PY - 2008 T1 - The role of timing in shaping information processing in neural systems TI - The role of timing in shaping information processing in neural systems UR - https://digitalcollections.ohsu.edu/record/338/files/339_etd.pdf Y1 - 2008 ER -