000000345 001__ 345 000000345 005__ 20260305145958.0 000000345 0247_ $$2DOI$$a10.6083/M48S4MVD 000000345 037__ $$aETD 000000345 245__ $$aThe effects of high- and low-carbohydrate weight loss diets on bone health in overweight and obese adults 000000345 260__ $$bOregon Health and Science University 000000345 269__ $$a2008 000000345 336__ $$aThesis 000000345 502__ $$bM.S. 000000345 520__ $$aThis study examined the effects of two six‑month weight‑loss diets—one high‑carbohydrate and one low‑carbohydrate with higher protein and fat—on urinary calcium excretion, bone turnover, and bone quality. We hypothesized that the low‑carbohydrate diet would increase urinary calcium loss, elevate bone resorption (higher N‑telopeptide, lower BSAP), and reduce bone mineral content and density compared with the high‑carbohydrate diet. Participants completed dual‑energy X‑ray absorptiometry and biochemical assessments of bone turnover and calcium excretion. Findings from this investigation provide insight into how macronutrient composition during weight loss may influence calcium metabolism and skeletal health. 000000345 540__ $$fCC BY 000000345 542__ $$fIn copyright - single owner 000000345 650__ $$aOverweight$$036327 000000345 650__ $$aBone Remodeling$$029352 000000345 650__ $$aDiet$$017776 000000345 650__ $$aCalcium$$015963 000000345 650__ $$aBone Density$$028469 000000345 650__ $$aNutrients$$012949 000000345 650__ $$aBone Resorption$$015734 000000345 650__ $$aBone Density$$028469 000000345 650__ $$aDiet, Reducing$$017782 000000345 650__ $$aDiet, Carbohydrate-Restricted$$036410 000000345 6531_ $$abone mineral density 000000345 6531_ $$abone mineral content 000000345 691__ $$aSchool of Medicine$$041369 000000345 692__ $$aDepartment of Dietetics and Nutrition$$041408 000000345 692__ $$aDepartment of Dietetics and Nutrition$$041408 000000345 7001_ $$aHall, Sherri$$uOregon Health and Science University$$041354 000000345 7201_ $$aStadler, Diane$$uOregon Health and Science University$$041354$$7Personal$$eMentor 000000345 8564_ $$9cc35271e-d224-44a7-a0f8-2220883cd7f2$$s642513$$uhttps://digitalcollections.ohsu.edu/record/345/files/346_etd.pdf$$ePublic$$205bfcf932bd72c0969659410869b127a$$31 000000345 905__ $$a/rest/prod/zg/64/tk/94/zg64tk941 000000345 909CO $$ooai:digitalcollections.ohsu.edu:345$$pstudent-work 000000345 956__ $$aGet Accessible Copy$$uhttps://ohsu.libwizard.com/f/requestaccessibledocument 000000345 980__ $$aTheses and Dissertations