000000354 001__ 354
000000354 005__ 20260410124446.0
000000354 0247_ $$2DOI$$a10.6083/M4416V1G
000000354 037__ $$aETD
000000354 245__ $$aAnnual coronary artery calcium progression and lifestyle modification
000000354 260__ $$bOregon Health and Science University
000000354 269__ $$a2009
000000354 336__ $$aThesis
000000354 502__ $$bM.P.H.
000000354 520__ $$aCoronary artery disease (CAD) involves progressive calcification of atherosclerotic plaque, measurable as coronary artery calcium (CAC) using multidetector computed tomography (MDCT). This study evaluated whether lifestyle modification influences CAC progression and whether changes in traditional CAD risk factors predict CAC outcomes. Among 22 participants with baseline and 1‑year 64‑MDCT scans, only 9.1% showed CAC reduction, while nearly 60% experienced more than 20% progression. Multivariable analyses found no significant associations between changes in LDL cholesterol, blood pressure, BMI, or functional capacity and CAC progression. Age, gender, and baseline CAC score were the strongest predictors of CAC change. Larger studies with longer follow‑up may clarify relationships between risk‑factor improvement and CAC progression.
000000354 540__ $$fCC BY
000000354 542__ $$fIn copyright - single owner
000000354 650__ $$aCoronary Artery Disease$$017109
000000354 650__ $$aCarotid Stenosis$$029505
000000354 650__ $$aLife Style$$021503
000000354 650__ $$aBody Mass Index$$028801
000000354 650__ $$aCholesterol, LDL$$021560
000000354 650__ $$aBlood Pressure$$015669
000000354 650__ $$aPlaque, Atherosclerotic$$039118
000000354 691__ $$aSchool of Medicine$$041369
000000354 692__ $$aDepartment of Public Health and Preventive Medicine$$041444
000000354 7001_ $$aFairbanks, Allison$$uOregon Health and Science University$$041354
000000354 7201_ $$aShannon, Jackilen$$uOregon Health and Science University$$041354$$7Personal$$eAdvisor
000000354 8564_ $$959f68545-5ae7-4eb4-8471-7520535695e3$$s323944$$uhttps://digitalcollections.ohsu.edu/record/354/files/355_etd.pdf$$ePublic$$20c67c304339c98edb553c0b0df1fd524$$31
000000354 901__ $$a<p>These documents are archival records. They are retained for historical reference only. </p><p><b>Need an accessible version? Use the ‘Get Accessible Copy’ link above.</b></p>
000000354 905__ $$a/rest/prod/66/82/x3/93/6682x3930
000000354 909CO $$ooai:digitalcollections.ohsu.edu:354$$pstudent-work
000000354 956__ $$aGet Accessible Copy$$uhttps://ohsu.libwizard.com/f/requestaccessibledocument
000000354 980__ $$aTheses and Dissertations