TY  - THES
AB  - Chronic inflammation may contribute to prostate cancer development and progression, with elevated interleukin‑6 (IL‑6) and C‑reactive protein (CRP) associated with poorer outcomes. Omega‑3 (n‑3) fatty acids, known for anti‑inflammatory effects, may reduce prostate cancer risk by lowering these markers. This secondary analysis examined relationships among inflammation, prostate cancer status, and n‑3 fatty acid levels using data from a case‑control study. Plasma IL‑6 and CRP were measured in prostate cancer cases (n=121) and biopsy‑negative controls (n=240), and erythrocyte EPA and DHA were quantified via gas chromatography–mass spectrometry. This study aimed to evaluate inflammatory profiles and the potential modifying role of n‑3 fatty acids in prostate cancer.
AD  - Oregon Health and Science University
AU  - Feifers, Julie
DA  - 2009
DO  - 10.6083/M40C4SQ2
DO  - DOI
ED  - Shannon, Jackilen
ED  - Advisor
ID  - 355
KW  - Prostatic Neoplasms
KW  - C-Reactive Protein
KW  - Interleukin-6
KW  - Prostatitis
KW  - Fatty Acids
KW  - Case-Control Studies
KW  - Gas Chromatography-Mass Spectrometry
KW  - Anti-Inflammatory Agents
KW  - Inflammation
KW  - Fatty Acids, Omega-3
L1  - https://digitalcollections.ohsu.edu/record/355/files/356_etd.pdf
L2  - https://digitalcollections.ohsu.edu/record/355/files/356_etd.pdf
L4  - https://digitalcollections.ohsu.edu/record/355/files/356_etd.pdf
LK  - https://digitalcollections.ohsu.edu/record/355/files/356_etd.pdf
N2  - Chronic inflammation may contribute to prostate cancer development and progression, with elevated interleukin‑6 (IL‑6) and C‑reactive protein (CRP) associated with poorer outcomes. Omega‑3 (n‑3) fatty acids, known for anti‑inflammatory effects, may reduce prostate cancer risk by lowering these markers. This secondary analysis examined relationships among inflammation, prostate cancer status, and n‑3 fatty acid levels using data from a case‑control study. Plasma IL‑6 and CRP were measured in prostate cancer cases (n=121) and biopsy‑negative controls (n=240), and erythrocyte EPA and DHA were quantified via gas chromatography–mass spectrometry. This study aimed to evaluate inflammatory profiles and the potential modifying role of n‑3 fatty acids in prostate cancer.
PB  - Oregon Health and Science University
PY  - 2009
T1  - Omega-3 fatty acids, inflammation, and outcome in men with and without prostate cancer
TI  - Omega-3 fatty acids, inflammation, and outcome in men with and without prostate cancer
UR  - https://digitalcollections.ohsu.edu/record/355/files/356_etd.pdf
Y1  - 2009
ER  -