000000355 001__ 355
000000355 005__ 20260303075857.0
000000355 0247_ $$2DOI$$a10.6083/M40C4SQ2
000000355 037__ $$aETD
000000355 245__ $$aOmega-3 fatty acids, inflammation, and outcome in men with and without prostate cancer
000000355 260__ $$bOregon Health and Science University
000000355 269__ $$a2009
000000355 336__ $$aThesis
000000355 502__ $$bM.S.
000000355 520__ $$aChronic inflammation may contribute to prostate cancer development and progression, with elevated interleukin‑6 (IL‑6) and C‑reactive protein (CRP) associated with poorer outcomes. Omega‑3 (n‑3) fatty acids, known for anti‑inflammatory effects, may reduce prostate cancer risk by lowering these markers. This secondary analysis examined relationships among inflammation, prostate cancer status, and n‑3 fatty acid levels using data from a case‑control study. Plasma IL‑6 and CRP were measured in prostate cancer cases (n=121) and biopsy‑negative controls (n=240), and erythrocyte EPA and DHA were quantified via gas chromatography–mass spectrometry. This study aimed to evaluate inflammatory profiles and the potential modifying role of n‑3 fatty acids in prostate cancer.
000000355 540__ $$fCC BY
000000355 542__ $$fIn copyright - single owner
000000355 650__ $$aProstatic Neoplasms$$024731
000000355 650__ $$aC-Reactive Protein$$015943
000000355 650__ $$aInterleukin-6$$028703
000000355 650__ $$aProstatitis$$024732
000000355 650__ $$aFatty Acids$$018911
000000355 650__ $$aCase-Control Studies$$028826
000000355 650__ $$aGas Chromatography-Mass Spectrometry$$021854
000000355 650__ $$aAnti-Inflammatory Agents$$014841
000000355 650__ $$aInflammation$$020800
000000355 650__ $$aFatty Acids, Omega-3$$028474
000000355 691__ $$aSchool of Medicine$$041369
000000355 692__ $$aGraduate Programs in Human Nutrition$$041470
000000355 7001_ $$aFeifers, Julie$$uOregon Health and Science University$$041354
000000355 7201_ $$aShannon, Jackilen$$uOregon Health and Science University$$041354$$7Personal$$eAdvisor
000000355 8564_ $$96d36ef99-27c5-4a04-80f2-0ecbff0adb87$$s1128988$$uhttps://digitalcollections.ohsu.edu/record/355/files/356_etd.pdf$$ePublic$$261816948d17fa543540169294ebf5325$$31
000000355 905__ $$a/rest/prod/7p/88/cg/53/7p88cg53c
000000355 909CO $$ooai:digitalcollections.ohsu.edu:355$$pstudent-work
000000355 956__ $$aGet Accessible Copy$$uhttps://ohsu.libwizard.com/f/requestaccessibledocument
000000355 980__ $$aTheses and Dissertations