Metabolic Detoxication, Phase II

Metabolic Detoxication, Conjugative
Metabolic Detoxification, Phase II
Phase II Detoxification
Conjugative Metabolic Detoxication
Conjugative Metabolic Detoxications
Detoxication, Conjugative Metabolic
Detoxications, Conjugative Metabolic
Detoxification, Phase II
Detoxifications, Phase II
Metabolic Detoxications, Conjugative
Phase II Detoxifications

The conjugation of exogenous substances with various hydrophilic substituents to form water soluble products that are excretable in URINE. Phase II modifications include GLUTATHIONE conjugation; ACYLATION; and AMINATION. Phase II enzymes include GLUTATHIONE TRANSFERASE and GLUCURONOSYLTRANSFERASE. In a sense these reactions detoxify phase I reaction products.
2006