000000396 001__ 396
000000396 005__ 20250424232520.0
000000396 0247_ $$2DOI$$a10.6083/M4PN93KV
000000396 037__ $$aETD
000000396 245__ $$aOptimization of image processing for mouse pharmacological magentic resonance imaging data
000000396 260__ $$bOregon Health and Science University
000000396 269__ $$a2009
000000396 336__ $$aCapstone
000000396 502__ $$bM.B.I.
000000396 502__ $$gBiomedical Informatics
000000396 520__ $$aNew imaging techniques, such as pharmacological magnetic resonance imaging (phMRI) permit measurement of in vivo changes in the brain after drug administration. However, there are numerous challenges when trying to apply this technique to commonly used  animal models of disease, such as the mouse. This capstone project focuses on some of the data analysis issues faced when trying to analyze high-resolution mouse phMRI data. Many of the problems encountered were due to the small size of the mouse brain in  comparison to the human brain and the fact that most available MRI software is designed for human data. This work is part of a larger project designed to measure changes in the mouse brain after alcohol administration.
000000396 540__ $$fCC BY
000000396 542__ $$fIn copyright - single owner
000000396 650__ $$aMagnetic Resonance Imaging$$021747
000000396 650__ $$aMice$$036842
000000396 650__ $$aEthanol$$014406
000000396 650__ $$aBrain$$015788
000000396 691__ $$aSchool of Medicine$$041369
000000396 692__ $$aDepartment of Medical Informatics and Clinical Epidemiology$$041422
000000396 7001_ $$aDingman, Cheryl$$uOregon Health and Science University$$041354
000000396 7201_ $$aBoudreau, Eilis$$uOregon Health and Science University$$041354$$7Personal$$eAcademic Advisor
000000396 8564_ $$9fb27a4bd-79c3-4197-8ac5-8e2f29773662$$s289145$$uhttps://digitalcollections.ohsu.edu/record/396/files/397_etd.pdf$$ePublic$$258882f63b3251cd15d4022448ce0c176$$31
000000396 905__ $$a/rest/prod/mw/22/v5/45/mw22v545k
000000396 909CO $$ooai:digitalcollections.ohsu.edu:396$$pstudent-work
000000396 980__ $$aBiomedical Informatics