000000405 001__ 405 000000405 005__ 20260302112055.0 000000405 0247_ $$2DOI$$a10.6083/M4J1014B 000000405 037__ $$aETD 000000405 245__ $$aFolate and prostate cancer a case-control study 000000405 260__ $$bOregon Health and Science University 000000405 269__ $$a2009 000000405 336__ $$aThesis 000000405 502__ $$bM.P.H. 000000405 520__ $$aProstate cancer is the most common cancer among men in the United States, yet few known risk factors are modifiable. Because geographic variation in prostate cancer incidence suggests environmental influences, folate has been investigated due to its role in one‑carbon metabolism, though prior findings have been inconsistent. This case‑control study examined folic acid levels in men undergoing prostate biopsy, comparing cases, biopsy‑negative controls, and clinic controls. Blood folic acid concentrations showed no significant association with prostate cancer risk, and correlations with reported dietary folate intake were low. These findings do not support a relationship between folate status and prostate cancer, highlighting the need for longitudinal studies to clarify timing and exposure effects. 000000405 540__ $$fCC BY 000000405 542__ $$fIn copyright - single owner 000000405 650__ $$aPteroylpolyglutamic Acids$$024875 000000405 650__ $$aProstatic Neoplasms$$024731 000000405 650__ $$aColorectal Neoplasms$$028197 000000405 650__ $$aFolic Acid$$019158 000000405 650__ $$aCase-Control Studies$$028826 000000405 650__ $$aMen's Health$$037897 000000405 651__ $$aUnited States$$041167 000000405 6531_ $$aprostate cancer 000000405 691__ $$aSchool of Medicine$$041369 000000405 692__ $$aDepartment of Public Health and Preventive Medicine$$041444 000000405 7001_ $$aLinz, Rachel$$uOregon Health and Science University$$041354 000000405 8564_ $$903969699-1b22-4f52-aef7-971a4f6cbfb1$$s350814$$uhttps://digitalcollections.ohsu.edu/record/405/files/406_etd.pdf$$ePublic$$250e373e735d4cab23ee98256778050f6$$31 000000405 905__ $$a/rest/prod/hh/63/sv/91/hh63sv915 000000405 909CO $$ooai:digitalcollections.ohsu.edu:405$$pstudent-work 000000405 956__ $$aGet Accessible Copy$$uhttps://ohsu.libwizard.com/f/requestaccessibledocument 000000405 980__ $$aTheses and Dissertations