TY - GEN N2 - Increasing evidence suggests that greater maternal adiposity during pregnancy is related to offspring risk for mental health disorders, although the mechanisms through which these effects are conveyed remain poorly understood. One hypothesis is that alterations in maternal concentrations of adipokines such as leptin and adiponectin may explain this association. Leptin and adiponectin influence the in-utero environment and glucoregulation in the parent and child, which has implications for fetal development and infant psychopathology.  The goal of the current study was to explore the mechanisms through which prenatal adipokines (leptin and adiponectin) influence the relationship between prenatal adiposity and infant negative affect.   DO - 10.6083/bpxhc41296 DO - doi AB - Increasing evidence suggests that greater maternal adiposity during pregnancy is related to offspring risk for mental health disorders, although the mechanisms through which these effects are conveyed remain poorly understood. One hypothesis is that alterations in maternal concentrations of adipokines such as leptin and adiponectin may explain this association. Leptin and adiponectin influence the in-utero environment and glucoregulation in the parent and child, which has implications for fetal development and infant psychopathology.  The goal of the current study was to explore the mechanisms through which prenatal adipokines (leptin and adiponectin) influence the relationship between prenatal adiposity and infant negative affect.   AD - Oregon Health and Science University T1 - Adipokines measured prenatally and at birth are associated with infant negative affect ED - Sullivan, Elinor ED - Gustafsson, Hanna ED - Young, Anna ED - Ablow, Jennifer ED - Nigg, Joel ED - Collaborator ED - Collaborator ED - Collaborator ED - Collaborator ED - Collaborator DA - 2023-07-19 AU - Molloy, Kelly L1 - https://digitalcollections.ohsu.edu/record/41296/files/ResearchWeek.2023.Molloy.Kelly.pdf PB - Oregon Health and Science University LA - eng PY - 2023-07-19 ID - 41296 L4 - https://digitalcollections.ohsu.edu/record/41296/files/ResearchWeek.2023.Molloy.Kelly.pdf KW - Pregnancy KW - Child Development KW - Adiposity KW - Adipokines KW - Mental Health KW - Developmental Biology KW - Mental Disorders KW - Fetal Development KW - Pregnancy KW - Obesity, Maternal KW - Temperament KW - Infant Behavior KW - early childhood development KW - infant development KW - infant temperament TI - Adipokines measured prenatally and at birth are associated with infant negative affect Y1 - 2023-07-19 L2 - https://digitalcollections.ohsu.edu/record/41296/files/ResearchWeek.2023.Molloy.Kelly.pdf LK - https://digitalcollections.ohsu.edu/record/41296/files/ResearchWeek.2023.Molloy.Kelly.pdf UR - https://digitalcollections.ohsu.edu/record/41296/files/ResearchWeek.2023.Molloy.Kelly.pdf ER -