@article{IR,
      author = {Lira Da Silva, Andre and Aslan, Joseph E. and McCarty,  Owen J.},
      url = {http://digitalcollections.ohsu.edu/record/41305},
      title = {Effects of bacteria lipopolysaccharides on the activation  and activity of coagulation factor XII},
      publisher = {Oregon Health and Science University},
      abstract = {Lipopolysaccharide (LPS), the major outer wall component  of Gram-negative bacteria, plays a critical role in the  pathogenesis of sepsis and are known to contribute to the  development of disseminated intravascular coagulation (DIC)  syndrome. Since LPS aggregates are negatively charged, we  hypothesized that LPS may directly interact with and  activate the contact pathway coagulation factor (F) XII as  part of the pathogenesis of DIC. This project aims to  investigate the mechanisms of interaction and activation of  FXII by LPS chemotypes.},
      number = {IR},
      doi = {https://doi.org/10.6083/bpxhc41305},
      recid = {41305},
      address = {2023-07-20},
}