TY - GEN N2 - Cannabis is the most frequently used federally illicit substance in pregnancy. The available human literature suggests that infants exposed to cannabis in pregnancy display signs of impaired neurodevelopment, including altered visual perception, exaggerated response to stimuli, and a high-pitched cry. Results from human studies are often confounded and limited by retrospective observational data, thus a relevant, translational animal model is needed. The objective of this study is to define the impact of chronic contemporary THC exposure on infant sensorimotor development and socioemotional behavior in a rhesus macaque model. DO - 10.6083/bpxhc41308 DO - doi AB - Cannabis is the most frequently used federally illicit substance in pregnancy. The available human literature suggests that infants exposed to cannabis in pregnancy display signs of impaired neurodevelopment, including altered visual perception, exaggerated response to stimuli, and a high-pitched cry. Results from human studies are often confounded and limited by retrospective observational data, thus a relevant, translational animal model is needed. The objective of this study is to define the impact of chronic contemporary THC exposure on infant sensorimotor development and socioemotional behavior in a rhesus macaque model. AD - Oregon Health and Science University AD - Oregon Health and Science University AD - Oregon Health and Science University T1 - Chronic prenatal delta-9-tetrahydrocannabinol exposure impacts offspring behavior in rhesus macaques ED - Lo, Jamie ED - Collaborator DA - 2023-07-20 AU - Hagen, Olivia AU - Graham, Jason A. AU - Sullivan, Elinor A. L1 - https://digitalcollections.ohsu.edu/record/41308/files/ResearchWeek.2023.Hagen.Olivia.pdf PB - Oregon Health and Science University LA - eng PY - 2023-07-20 ID - 41308 L4 - https://digitalcollections.ohsu.edu/record/41308/files/ResearchWeek.2023.Hagen.Olivia.pdf KW - Neurosciences KW - Developmental Biology KW - Cannabis KW - Prenatal Exposure Delayed Effects KW - Substance-Related Disorders KW - Marijuana Abuse KW - Marijuana Use KW - delta-9-hydrocannabinol KW - prenatal cannabis exposure KW - maternal cannabis use KW - THC KW - pregnancy outcomes TI - Chronic prenatal delta-9-tetrahydrocannabinol exposure impacts offspring behavior in rhesus macaques Y1 - 2023-07-20 L2 - https://digitalcollections.ohsu.edu/record/41308/files/ResearchWeek.2023.Hagen.Olivia.pdf LK - https://digitalcollections.ohsu.edu/record/41308/files/ResearchWeek.2023.Hagen.Olivia.pdf UR - https://digitalcollections.ohsu.edu/record/41308/files/ResearchWeek.2023.Hagen.Olivia.pdf ER -