000041308 001__ 41308
000041308 005__ 20240328140555.0
000041308 0247_ $$2doi$$a10.6083/bpxhc41308
000041308 037__ $$aIR
000041308 041__ $$aeng
000041308 245__ $$aChronic prenatal delta-9-tetrahydrocannabinol exposure impacts offspring behavior in rhesus macaques
000041308 260__ $$bOregon Health and Science University
000041308 269__ $$a2023-07-20
000041308 336__ $$aAbstract
000041308 520__ $$aCannabis is the most frequently used federally illicit substance in pregnancy. The available human literature suggests that infants exposed to cannabis in pregnancy display signs of impaired neurodevelopment, including altered visual perception, exaggerated response to stimuli, and a high-pitched cry. Results from human studies are often confounded and limited by retrospective observational data, thus a relevant, translational animal model is needed. The objective of this study is to define the impact of chronic contemporary THC exposure on infant sensorimotor development and socioemotional behavior in a rhesus macaque model.
000041308 540__ $$fCC BY
000041308 542__ $$fIn copyright - joint owners
000041308 650__ $$aNeurosciences$$022870
000041308 650__ $$aDevelopmental Biology$$028463
000041308 650__ $$aCannabis$$016026
000041308 650__ $$aPrenatal Exposure Delayed Effects$$024568
000041308 650__ $$aSubstance-Related Disorders$$032029
000041308 650__ $$aMarijuana Abuse$$016027
000041308 650__ $$aMarijuana Use$$012385
000041308 6531_ $$adelta-9-hydrocannabinol
000041308 6531_ $$aprenatal cannabis exposure
000041308 6531_ $$amaternal cannabis use
000041308 6531_ $$aTHC
000041308 6531_ $$apregnancy outcomes
000041308 692__ $$aDivision of Reproductive & Developmental Sciences$$041468
000041308 692__ $$aOregon National Primate Research Center$$041497
000041308 7001_ $$aHagen, Olivia$$uOregon Health and Science University$$041354
000041308 7001_ $$aGraham, Jason A.$$uOregon Health and Science University$$041354
000041308 7001_ $$aSullivan, Elinor A.$$uOregon Health and Science University$$041354
000041308 711__ $$aResearch Week$$uOregon Health and Science University$$d2023
000041308 7201_ $$aLo, Jamie$$uOregon Health and Science University$$eCollaborator$$7Personal
000041308 8564_ $$9a78612e5-7720-4d52-94e2-eab7b1328331$$s71967$$uhttps://digitalcollections.ohsu.edu/record/41308/files/ResearchWeek.2023.Hagen.Olivia.pdf
000041308 980__ $$aResearch Week
000041308 981__ $$aPublished$$b2023-07-20