000041322 001__ 41322
000041322 005__ 20240412101744.0
000041322 0247_ $$2doi$$a10.6083/bpxhc41322
000041322 037__ $$aIR
000041322 041__ $$aeng
000041322 245__ $$aMetabolic patterns in female SIV-infected rhesus macaques after consistent antiretroviral therapy
000041322 260__ $$bOregon Health and Science University
000041322 269__ $$a2023-07-21
000041322 336__ $$aAbstract
000041322 520__ $$aHIV/AIDS is a chronic disease that causes increased inflammation and decreased immune function within people living with HIV (PLWH). A majority of PLWH are women; however, very little research has focused on the unique metabolic changes that occur in women living with HIV (WLWH). While HIV was once considered fatal, current antiretroviral therapy (ART) treatments can effectively control viral loads and allow PLWH to have near-normal life expectancy. This causes WLWH to experience age-related hormonal changes known to have systemic metabolic effects, such as estrogen deficiency associated with menopause. Increased age, inflammation, and hormonal changes are all associated with similar comorbidities, leaving WLWH at higher risk for developing chronic metabolic disorders such as obesity, diabetes, and cardiovascular disease.
000041322 540__ $$fCC BY
000041322 542__ $$fIn copyright - joint owners
000041322 650__ $$aHIV$$020258
000041322 650__ $$aSimian Immunodeficiency Virus$$028304
000041322 650__ $$aAntiretroviral Therapy, Highly Active$$033014
000041322 650__ $$aPrimates$$024593
000041322 650__ $$aMetabolism$$022101
000041322 650__ $$aPublic Health$$024885
000041322 650__ $$aPathology$$023652
000041322 650__ $$aArt$$015078
000041322 650__ $$aMacaca mulatta$$021724
000041322 6531_ $$aSIV
000041322 6531_ $$anon-human primate
000041322 6531_ $$aPLWH
000041322 6531_ $$aWLWH
000041322 6531_ $$awomen living with HIV
000041322 6531_ $$apeople living with HIV
000041322 692__ $$aOregon National Primate Research Center$$041497
000041322 7001_ $$aHofmeister, Heather$$uOregon Health and Science University$$041354
000041322 7001_ $$aTakahashi, Diana$$uOregon Health and Science University$$041354
000041322 7001_ $$aSauter, Kristin$$uOregon Health and Science University$$041354
000041322 7001_ $$aWebb, Gabriela$$uOregon Health and Science University$$041354
000041322 7001_ $$aVarlamov, Oleg$$uOregon Health and Science University$$041354
000041322 7001_ $$aKievit, Paul$$uOregon Health and Science University$$041354
000041322 7001_ $$aSacha, Jonah$$uOregon Health and Science University$$041354
000041322 711__ $$aResearch Week$$uOregon Health and Science University$$d2023
000041322 7201_ $$7Personal
000041322 8564_ $$9a5f0f08b-28e1-4893-a454-e1abbf65b7eb$$s121013$$uhttps://digitalcollections.ohsu.edu/record/41322/files/ResearchWeek.2023.Hofmeister.Heather.pdf
000041322 980__ $$aResearch Week
000041322 981__ $$aPublished$$b2023-07-21