000041330 001__ 41330 000041330 005__ 20240329104524.0 000041330 0247_ $$2doi$$a10.6083/bpxhc41330 000041330 037__ $$aIR 000041330 041__ $$aeng 000041330 245__ $$aComputational tools for predicting microbial function from gut metagenomes 000041330 260__ $$bOregon Health and Science University 000041330 269__ $$a2023-07-21 000041330 336__ $$aAbstract 000041330 520__ $$aThe gut microbiome is involved in promoting or inhibiting (protecting against or contributing to the development of) many diseases, such as diabetes, inflammatory bowel disease, obesity, and cardiovascular disease, depending on the functions that the microbes encode. This study will discuss the available frameworks for predicting metagenomic functions, as well as provide key considerations for selecting the most appropriate tool given the question and data at hand. 000041330 540__ $$fCC BY 000041330 542__ $$fIn copyright - single owner 000041330 650__ $$aGenomics$$033016 000041330 650__ $$aComputational Biology$$031511 000041330 650__ $$aGastrointestinal Microbiome$$011348 000041330 6531_ $$abioinformatics 000041330 6531_ $$ashotgun metagenomics 000041330 6531_ $$amicrobial functional predictions 000041330 6531_ $$agut microbiome 000041330 691__ $$aSchool of Medicine$$041369 000041330 692__ $$aDepartment of Medical Informatics and Clinical Epidemiology$$041422 000041330 7001_ $$aTurner, Christina$$uOregon Health and Science University$$041354 000041330 711__ $$aResearch Week$$uOregon Health and Science University$$d2023 000041330 7201_ $$aMcWeeney, Shannon$$uKnight ISR Research$$7Personal 000041330 8564_ $$90413d15b-3abc-4c9a-96f3-e7f4ad60b0e2$$s167472$$uhttps://digitalcollections.ohsu.edu/record/41330/files/ResearchWeek.2023.Turner.Christina.pdf 000041330 980__ $$aResearch Week 000041330 981__ $$aPublished$$b2023-07-21